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J L Aschner

Explore the profile of J L Aschner including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 390
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Recent Articles
1.
Aschner J, Aschner M
Open Toxicol J . 2019 Jun; 1:1-9. PMID: 31178939
Mechanistic studies on the effects of MeHg in the central nervous system (CNS) have been limited to morphology, substrate uptake and macromolecular synthesis, differentiation, and changes in gene expression during...
2.
Aschner J, Gien J, Ambalavanan N, Kinsella J, Konduri G, Lakshminrusimha S, et al.
J Perinatol . 2016 May; 36 Suppl 2:S32-6. PMID: 27225964
Future priorities for the management of hypoxemic respiratory failure (HRF) and pulmonary hypertension include primary prevention of neonatal lung diseases, 'precision medicine' and translating promising clinical and preclinical research into...
3.
Ambalavanan N, Aschner J
J Perinatol . 2016 May; 36 Suppl 2:S20-7. PMID: 27225961
While diagnoses of hypoxemic respiratory failure (HRF) and pulmonary hypertension (PH) in preterm infants may be based on criteria similar to those in term infants, management approaches often differ. In...
4.
Matthews M, Aschner J, Stark A, Moore P, Slaughter J, Steele S, et al.
J Perinatol . 2016 May; 36(9):779-83. PMID: 27171764
Objective: This study examined the association between increased early oxidative stress, measured by F2-isoprostanes (IsoPs), and respiratory morbidity at term equivalent age and neurological impairment at 12 months of corrected...
5.
Dennis K, Aschner J, Milatovic D, Schmidt J, Aschner M, Kaplowitz M, et al.
Am J Physiol Lung Cell Mol Physiol . 2009 Jul; 297(4):L596-607. PMID: 19592458
Recently, we reported that reactive oxygen species (ROS) generated by NADPH oxidase (NOX) contribute to aberrant responses in pulmonary resistance arteries (PRAs) of piglets exposed to 3 days of hypoxia...
6.
Durand D, Asselin J, Hudak M, Aschner J, McArtor R, Cleary J, et al.
J Perinatol . 2001 Sep; 21(4):221-9. PMID: 11533838
Objective: To evaluate the feasibility of conducting a prospective, randomized trial comparing early high-frequency oscillatory ventilation (HFOV) to synchronized intermittent mandatory ventilation (SIMV) in very low birth weight (VLBW) premature...
7.
Aschner J, Kovacs N, Perciaccante J, Figueroa J, Thrikawala N, Robins G, et al.
Am J Physiol . 1999 Jul; 277(1):H371-9. PMID: 10409217
We determined the expression and functional correlate of in vitro transfection with a recombinant adenoviral vector encoding the gene for bovine endothelial nitric oxide synthase (AdCMVeNOS) or Escherichia coli beta-galactosidase...
8.
Fuloria M, Friedberg M, DuRant R, Aschner J
Pediatrics . 1998 Dec; 102(6):1401-6. PMID: 9832576
Background: A retrospective medical record review of 13 consecutive, hyperglycemic, extremely low birth weight (ELBW) infants treated with continuous insulin infusions revealed a 14- to 24-hour delay (mean, 19 hours)...
9.
Aschner M, Conklin D, Aschner J
Brain Res . 1998 Jan; 770(1-2):289-93. PMID: 9372231
Metallothionein (MT) mRNA was determined in rat astrocyte cultures in response to ethanol (EtOH). MT-I mRNA was significantly increased after 6 h exposure to isosmotic EtOH, but not hyperosmotic EtOH....
10.
Aschner J, Lum H, Fletcher P, Malik A
J Cell Physiol . 1997 Nov; 173(3):387-96. PMID: 9369952
We determined whether activation of phosphatidylinositol-specific phospholipase C (PI-PLC) and a subsequent increase in cytosolic calcium concentration ([Ca2+]i) was an obligatory signaling event mediating the increase in transendothelial permeability induced...