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J Kottakis

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Recent Articles
1.
Muir J, Benhamou D, Cuvelier A, Le Gros V, Overend T, Till D, et al.
Int J Clin Pract . 2004 Jun; 58(5):457-64. PMID: 15206501
Evaluation of patients with chronic obstructive pulmonary disease (COPD) often includes the use of post-bronchodilator reversibility testing to guide treatment decisions. Recommendations for reversibility testing differ and there is no...
2.
Dahl R, Creemers J, van Noord J, Sips A, Della Cioppa G, Thomson M, et al.
Respiration . 2004 Mar; 71(2):126-33. PMID: 15031566
Background: For maximum treatment compliance there is a need to provide asthma patients with devices that suit their particular preferences. The Foradil Certihaler is a novel multi-dose dry powder inhaler...
3.
Mitchell C, Jenkins C, Scicchitano R, Rubinfeld A, Kottakis J
Pulm Pharmacol Ther . 2003 Jul; 16(5):299-306. PMID: 12877821
This double-blind, randomised, multi-centre, parallel-group study compared the effect of adding Foradil (formoterol fumarate) to existing medium-high doses of inhaled corticosteroids (ICS) with that of doubling the dose of ICS...
4.
Benhamou D, Cuvelier A, Muir J, Leclerc V, Le Gros V, Kottakis J, et al.
Respir Med . 2001 Oct; 95(10):817-21. PMID: 11601748
Formoterol fumarate is a beta2-agonist bronchodilator that combines a fast onset of action with a long duration of action. Its fast onset of action is well documented in asthma but...
5.
Kottakis J, Wood R, Le Gros V, Della Cioppa G
Int J Clin Pract . 2001 Oct; 55(7):476-9. PMID: 11594259
Salmeterol and formoterol are both beta 2-agonist bronchodilators with a long duration of action and are often classified together, yet they are distinctly different in their pharmacology. Recent evidence suggests...
6.
Eliraz A, Ramirez-Rivera A, Ferranti P, Holzer R, Garcia J, Turcotte C, et al.
Int J Clin Pract . 2001 May; 55(3):164-70. PMID: 11351769
This randomised, multicentre, parallel-group study compared the clinical efficacy and ease of handling of two dry powder inhalers delivering the long-acting beta 2-agonist formoterol. After run-in, 200 asthmatics on treatment...
7.
DUrzo A, De Salvo M, Ramirez-Rivera A, Almeida J, Sichletidis L, Rapatz G, et al.
Chest . 2001 May; 119(5):1347-56. PMID: 11348938
Study Objectives: To compare the efficacy of adding formoterol or salbutamol to regular ipratropium bromide treatment in COPD patients whose conditions were suboptimally controlled with ipratropium bromide alone. Design: A...
8.
Sichletidis L, Kottakis J, Marcou S, Constantinidis T, Antoniades A
Int J Clin Pract . 2000 Feb; 53(3):185-8. PMID: 10665129
We studied 27 patients with stable chronic obstuctive pulmonary disease (COPD) in a randomised, single-blind, within-patient, placebo-controlled clinical study. Each patient was assigned on six separate days to receive one...
9.
Lotvall J, Mellen A, Arvidsson P, Palmqvist M, Radielovic P, Kottakis J, et al.
Can Respir J . 1999 Nov; 6(5):412-6. PMID: 10572207
Background: In many countries, two dry powder formulations of inhaled formoterol are available for clinical use; one uses a single-dose device (Foradil, Aerolizer), and the other uses a multiple-dose device...
10.
Bouros D, Bachlitzanakis N, Kottakis J, Pfister P, Polychronopoulos V, Papadakis E, et al.
Eur Respir J . 1999 Oct; 14(3):627-32. PMID: 10543286
A total of 132 adult asthmatics who were symptomatic on 500 microg x day(-1) inhaled beclomethasone dipropionate (BDP) were studied in an open-label randomized, parallel group, 12 week, clinical trial....