J K Pritchard
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Explore the profile of J K Pritchard including associated specialties, affiliations and a list of published articles.
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21
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12616
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Recent Articles
1.
Stahlschmidt M, Collin T, Fernandes D, Bar-Oz G, Belfer-Cohen A, Gao Z, et al.
Sci Rep
. 2019 May;
9(1):6628.
PMID: 31036834
Metagenomic analysis is a highly promising technique in paleogenetic research that allows analysis of the complete genomic make-up of a sample. This technique has successfully been employed to archaeological sediments,...
2.
An approximate likelihood for genetic data under a model with recombination and population splitting
Davison D, Pritchard J, Coop G
Theor Popul Biol
. 2009 Apr;
75(4):331-45.
PMID: 19362099
We describe a new approximate likelihood for population genetic data under a model in which a single ancestral population has split into two daughter populations. The approximate likelihood is based...
3.
Pemberton T, Jakobsson M, Conrad D, Coop G, Wall J, Pritchard J, et al.
Ann Hum Genet
. 2008 Jun;
72(Pt 4):535-46.
PMID: 18513279
When performing association studies in populations that have not been the focus of large-scale investigations of haplotype variation, it is often helpful to rely on genomic databases in other populations...
4.
Pritchard J, Donnelly P
Theor Popul Biol
. 2002 Feb;
60(3):227-37.
PMID: 11855957
Case-control tests for association are an important tool for mapping complex-trait genes. But population structure can invalidate this approach, leading to apparent associations at markers that are unlinked to disease...
5.
Pritchard J
Nat Genet
. 2001 Jun;
28(3):203-4.
PMID: 11431683
Association studies have rarely been used in plant genetics, in part because of the risk of false positives caused by population structure. A study of flowering time in maize makes...
6.
Pritchard J, Przeworski M
Am J Hum Genet
. 2001 Jun;
69(1):1-14.
PMID: 11410837
In this review, we describe recent empirical and theoretical work on the extent of linkage disequilibrium (LD) in the human genome, comparing the predictions of simple population-genetic models to available...
7.
Pritchard J
Am J Hum Genet
. 2001 Jun;
69(1):124-37.
PMID: 11404818
Little is known about the nature of genetic variation underlying complex diseases in humans. One popular view proposes that mapping efforts should focus on identification of susceptibility mutations that are...
8.
Beaumont M, Barratt E, Gottelli D, Kitchener A, Daniels M, Pritchard J, et al.
Mol Ecol
. 2001 Apr;
10(2):319-36.
PMID: 11298948
This paper describes a genetic analysis of wild-living cats in Scotland. Samples from 230 wild-living Scottish cats (including 13 museum skins) and 74 house cats from England and Scotland were...
9.
Rosenberg N, Woolf E, Pritchard J, Schaap T, Gefel D, Shpirer I, et al.
Proc Natl Acad Sci U S A
. 2001 Feb;
98(3):858-63.
PMID: 11158561
Unlinked autosomal microsatellites in six Jewish and two non-Jewish populations were genotyped, and the relationships among these populations were explored. Based on considerations of clustering, pairwise population differentiation, and genetic...
10.
Thomson R, Pritchard J, Shen P, Oefner P, Feldman M
Proc Natl Acad Sci U S A
. 2000 Jun;
97(13):7360-5.
PMID: 10861004
We consider a data set of DNA sequence variation at three Y chromosome genes (SMCY, DBY, and DFFRY) in a worldwide sample of human Y chromosomes. Between 53 and 70...