J J SPITZER
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Explore the profile of J J SPITZER including associated specialties, affiliations and a list of published articles.
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Articles
257
Citations
1257
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Recent Articles
1.
Spitzer J, SPITZER J
Alcohol
. 2000 Aug;
21(1):27-35.
PMID: 10946155
This study was directed at the role of tolerance to endotoxin (lipopolysaccharide, LPS) and ethanol (EtOH) intoxication in modulating hepatic nitric oxide (NO) production, and the demonstration of gender differences....
2.
Wang E, SPITZER J, Chamulitrat W
Nitric Oxide
. 1999 Aug;
3(3):244-53.
PMID: 10442856
We have examined the regulation of inducible nitric oxide synthase (iNOS) gene expression by ethanol in monolayers of DLD-1 cells, an epithelial cell line derived from human intestinal adenocarcinoma. Optimum...
3.
Bautista A, SPITZER J
Front Biosci
. 1999 Jul;
4:D589-95.
PMID: 10417056
These studies test the hypothesis that acute and chronic alcohol intoxication stimulate the release of oxygen-derived radicals in the liver. Male Sprague-Dawley rats received an intravenous bolus followed by continuous...
4.
5.
SPITZER J, Bautista A
Gastroenterology
. 1998 Oct;
115(2):494-6.
PMID: 9758537
No abstract available.
6.
Chamulitrat W, Carnal J, Reed N, SPITZER J
Am J Physiol
. 1998 May;
274(4):G653-61.
PMID: 9575846
Endotoxemia is associated with alcoholic liver diseases; however, the effect of endotoxin on the oxidation of ethanol is not known. We tested the hypothesis that endotoxin treatment enhances hepatic ethanol...
7.
Chamulitrat W, SPITZER J
Biochim Biophys Acta
. 1997 Jul;
1336(1):73-82.
PMID: 9271252
Reactive oxygen and nitrogen species have been implicated in the inflammation of the gastrointestinal tract. The objective of this study was to investigate mechanisms of free radical formation from the...
8.
Wang J, SPITZER J
Alcohol
. 1997 Jan;
14(1):99-105.
PMID: 9014030
This study examines the effects of chronic alcohol consumption on thymic apoptosis with or without pretreatment with E. coli lipopolysaccharide (LPS). Apoptotic cell death of thymocytes was monitored by DNA...
9.
Bautista A, SPITZER J
Alcohol Clin Exp Res
. 1996 Nov;
20(8):1395-400.
PMID: 8947315
This study tests two hypotheses: (1) prior exposure to LPS induces cross-tolerance for the hepatic effects of subsequent short-term alcohol intoxication; and (2) short-term alcohol intoxication renders the liver resistant...
10.
Chamulitrat W, SPITZER J
Alcohol Clin Exp Res
. 1996 Sep;
20(6):1065-70.
PMID: 8892528
Earlier studies showed that alcohol-fed animals were more susceptible than controls to injurious effects of endotoxin. Increased superoxide radical production by hepatocyte organelles, Kupffer cells, and neutrophils from alcohol-fed animals...