J J Oleynek
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Explore the profile of J J Oleynek including associated specialties, affiliations and a list of published articles.
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10
Citations
79
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Recent Articles
1.
Tracey W, Magee W, MASAMUNE H, Oleynek J, Hill R
Cardiovasc Res
. 1999 Jan;
40(1):138-45.
PMID: 9876326
Objective: The aim of this study was to characterize the adenosine A3 receptor agonist, N6-(3-chlorobenzyl)-5'-N-methylcarboxamidoadenosine (CB-MECA), evaluate its ability to reduce myocardial ischemia/reperfusion injury and determine the role of KATP-channel...
2.
Hill R, Oleynek J, Magee W, Knight D, Tracey W
J Mol Cell Cardiol
. 1998 May;
30(3):579-85.
PMID: 9515033
Although ischemic preconditioning (IP) in several species can be pharmacologically mimicked by selective adenosine A1 or A3 receptor agonists, it is currently unclear which receptor subtype (A1 and/or A3) is...
3.
Kennedy S, Sun D, Oleynek J, Hoth C, Kong J, Hill R
Biochem Biophys Res Commun
. 1998 Apr;
244(3):832-7.
PMID: 9535752
There has been considerable difficulty in defining distinct adrenomedullin (AM) binding sites and function in vivo. However, a rat adrenomedullin receptor (rAMR) and a putative human adrenomedullin receptor (hAMR) have...
4.
Barrow C, Oleynek J, Marinelli V, Sun H, Kaplita P, Sedlock D, et al.
J Antibiot (Tokyo)
. 1997 Nov;
50(9):729-33.
PMID: 9360616
A related group of compounds belonging to the antimycin class of antibiotics was found in culture broth produced by a Streptomyces species. The group includes known antimycins A1, A2, A3...
5.
Hill R, Oleynek J, Hoth C, Kiron M, Weng W, Wester R, et al.
J Pharmacol Exp Ther
. 1997 Jan;
280(1):122-8.
PMID: 8996189
The role of adenosine A1 and A3 receptors in mediating cardioprotection has been studied predominantly in rabbits, yet the pharmacological characteristics of rabbit adenosine A1 and A3 receptor subtypes are...
6.
Sawutz D, Krafte D, Oleynek J, Ault B
J Recept Signal Transduct Res
. 1995 Jul;
15(6):829-46.
PMID: 7584514
AMPA receptors may play an important role in acute and chronic neurodegenerative diseases. An assay for the specific binding of [3H]-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) to receptors in membranes from post-mortem human...
7.
Oleynek J, Sedlock D, Barrow C, Appell K, Casiano F, Haycock D, et al.
J Antibiot (Tokyo)
. 1994 Apr;
47(4):399-410.
PMID: 7515038
WIN 64821, a secondary metabolite produced by Aspergillus sp. (ATCC 74177) was found to inhibit radiolabeled substance P (SP) binding in a variety of tissues, including those of human origin....
8.
Meisheri K, Oleynek J, Puddington L
J Pharmacol Exp Ther
. 1991 Sep;
258(3):1091-7.
PMID: 1890613
Evidence from contractile, radioisotope ion flux and electrophysiological studies suggest that minoxidil sulfate (MNXS) acts as a K+ channel opener in vascular smooth muscle. This study was designed to examine...
9.
Meisheri K, Swirtz M, Purohit S, Khan S, Oleynek J
J Pharmacol Exp Ther
. 1991 Feb;
256(2):492-9.
PMID: 1993992
The mechanisms of pinacidil-induced direct vasodilation were studied in vitro in RMA and RAO. In RMA, pinacidil produced dose-dependent relaxations of norepinephrine (5 microM)-induced contractions with an IC50 of 0.2...
10.
Meisheri K, Dubray L, Oleynek J
J Pharmacol Methods
. 1990 Dec;
24(4):251-61.
PMID: 2292878
This study describes a sensitive in vitro relaxation assay using isolated rabbit mesenteric artery to detect the activity of a vasodilator as a K(+)-channel activator. Thus, comparison of several known...