J J Guinan Jr
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Explore the profile of J J Guinan Jr including associated specialties, affiliations and a list of published articles.
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1692
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Recent Articles
1.
Guinan Jr J, Lefler S, Buchman C, Goodman S, Lichtenhan J
Sci Rep
. 2021 May;
11(1):10380.
PMID: 34001971
A fundamental property of mammalian hearing is the conversion of sound pressure into a frequency-specific place of maximum vibration along the cochlear length, thereby creating a tonotopic map. The tonotopic...
2.
Lee C, Guinan Jr J, Rutherford M, Kaf W, Kennedy K, Buchman C, et al.
J Neurophysiol
. 2019 Jan;
121(3):1018-1033.
PMID: 30673362
Little is known about the spatial origins of auditory nerve (AN) compound action potentials (CAPs) evoked by moderate to intense sounds. We studied the spatial origins of AN CAPs evoked...
3.
Lichtenhan J, Wilson U, Hancock K, Guinan Jr J
Hear Res
. 2015 Sep;
333:216-224.
PMID: 26364824
Inhibition of cochlear amplifier gain by the medial olivocochlear (MOC) efferent system has several putative roles: aiding listening in noise, protection against damage from acoustic overexposure, and slowing age-induced hearing...
4.
Lichtenhan J, Hartsock J, Gill R, Guinan Jr J, Salt A
J Assoc Res Otolaryngol
. 2014 Feb;
15(3):395-411.
PMID: 24515339
Measurements of cochlear function with compound action potentials (CAPs), auditory brainstem responses, and otoacoustic emissions work well with high-frequency sounds but are problematic at low frequencies. We have recently shown...
5.
Cooper N, Guinan Jr J
J Physiol
. 2006 Aug;
576(Pt 1):49-54.
PMID: 16901947
Medial olivocochlear efferent (MOCE) neurones innervate the outer hair cells (OHCs) of the mammalian cochlea, and convey signals that are capable of controlling the sensitivity of the peripheral auditory system...
6.
Liberman M, Zuo J, Guinan Jr J
J Acoust Soc Am
. 2004 Oct;
116(3):1649-55.
PMID: 15478431
Distortion product otoacoustic emissions (DPOAEs) evoked by low-level tones are a sensitive indicator of outer hair cell (OHC) function. High-level DPOAEs are less vulnerable to cochlear insult, and their dependence...
7.
Brown M, de Venecia R, Guinan Jr J
Exp Brain Res
. 2003 Oct;
153(4):491-8.
PMID: 14557911
Medial olivocochlear (MOC) neurons project to outer hair cells (OHC), forming the efferent arm of a reflex that affects sound processing and offers protection from acoustic overstimulation. The central pathways...
8.
Cooper N, Guinan Jr J
J Physiol
. 2003 Mar;
548(Pt 1):307-12.
PMID: 12611913
Sound-evoked vibrations of the basilar membrane (BM) in anaesthetised guinea-pigs are shown to be affected over two distinct time scales by electrical stimulation of the medial olivocochlear efferent system: one...
9.
Stankovic K, Guinan Jr J
J Acoust Soc Am
. 2000 Aug;
108(2):664-78.
PMID: 10955633
It is often assumed that at frequencies in the tuning-curve tail there is a passive, constant coupling of basilar-membrane motion to inner hair cell (IHC) stereocilia. This paper shows changes...
10.
Lin T, Guinan Jr J
J Acoust Soc Am
. 2000 Jun;
107(5 Pt 1):2615-30.
PMID: 10830384
There has been no systematic study of auditory-nerve-fiber (ANF) responses to high-level clicks despite the advantages of clicks in revealing the natural resonances of a system. Cat single ANFs were...