J I Isenberg
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Explore the profile of J I Isenberg including associated specialties, affiliations and a list of published articles.
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Articles
146
Citations
1458
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Recent Articles
1.
Orloff M, Isenberg J, Wheeler H, Haynes K, Jinich-Brook H, Rapier R, et al.
Transplant Proc
. 2010 Dec;
42(10):4101-8.
PMID: 21168637
Background: Bleeding esophageal varices (BEV) in cirrhosis has been considered an indication for liver transplantation (LT). This issue was examined in a randomized controlled trial (RCT) of unselected, consecutive patients...
2.
Rao S, Sellers Z, Crombie D, Hogan D, Mann E, Childs D, et al.
Am J Physiol Gastrointest Liver Physiol
. 2003 Jul;
286(1):G95-G101.
PMID: 12881226
Luminal acidification provides the strongest physiological stimulus for duodenal HCO3- secretion. Various neurohumoral mechanisms are believed to play a role in acid-stimulated HCO3- secretion. Previous studies in the rat and...
3.
Repishti M, Hogan D, Pratha V, Davydova L, Donowitz M, Tse C, et al.
Am J Physiol Gastrointest Liver Physiol
. 2001 Jun;
281(1):G159-63.
PMID: 11408268
The proximal duodenal mucosa secretes HCO that serves to protect the epithelium from injury. In isolated human duodenal enterocytes in vitro, multiple luminal membrane proteins are involved in acid/base transport....
4.
Flemstrom G, Isenberg J
News Physiol Sci
. 2001 Jun;
16:23-8.
PMID: 11390942
The gastroduodenal mucosa is a dynamic barrier restricting entry of gastric acid and other potentially hostile luminal contents. Mucosal HCO3(-) is a key element in preventing epithelial damage, and knowledge...
5.
Pratha V, Hogan D, Martensson B, Bernard J, Zhou R, Isenberg J
Gastroenterology
. 2000 Jun;
118(6):1051-60.
PMID: 10833480
Background & Aims: The duodenum is a cystic fibrosis transmembrane conductance regulator (CFTR)-expressing epithelium with high bicarbonate secretory capacity. We aimed to define the role of CFTR in human duodenal...
6.
Pratha V, Thompson S, Hogan D, Paulus P, Dreilinger A, Barrett K, et al.
J Lab Clin Med
. 1998 Dec;
132(6):512-8.
PMID: 9851742
Duodenal mucosal bicarbonate secretion (DMBS) prevents acid-peptic damage and facilitates nutrient absorption. DMBS is diminished in patients with duodenal ulcers and is normalized after Helicobacter pylori eradication. The measurement of...
7.
Ainsworth M, Hogan D, Rapier R, Amelsberg M, Dreilinger A, Isenberg J
Scand J Gastroenterol
. 1998 Nov;
33(10):1039-46.
PMID: 9829357
Background: Duodenal mucosal bicarbonate secretion serves as a key defensive factor against mucosal injury. The purpose of the present study was to isolate human proximal duodenal enterocytes and identify their...
8.
Nyberg L, Pratha V, Hogan D, Rapier R, Koss M, Isenberg J
Dig Dis Sci
. 1998 Jul;
43(6):1205-10.
PMID: 9635609
The proximal duodenal epithelium secretes bicarbonate into an adherent mucus layer, thereby protecting the mucosa from injury by gastric acid and pepsin. While bicarbonate secretion is stimulated and inhibited by...
9.
Hogan D, Yao B, Isenberg J
Dig Dis Sci
. 1998 Mar;
43(1):120-5.
PMID: 9508512
Surface epithelial bicarbonate secretion protects the proximal duodenum from acid peptic injury. Cyclic adenosine monophosphate and calcium serve as intracellular mediators of intestinal transport. Experiments were performed to examine whether...
10.
Myers C, Hogan D, Yao B, Koss M, Isenberg J, Barrett K
Gastroenterology
. 1998 Mar;
114(3):527-35.
PMID: 9496943
Background & Aims: The gastroduodenal epithelium is protected from acid-peptic damage, in part, by its ability to secrete bicarbonate. Patients with duodenal ulcer disease have impaired proximal duodenal mucosal bicarbonate...