J Hayles
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Explore the profile of J Hayles including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
1555
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Recent Articles
1.
Wood V, Gwilliam R, Rajandream M, LYNE M, Lyne R, Stewart A, et al.
Nature
. 2002 Feb;
415(6874):871-80.
PMID: 11859360
We have sequenced and annotated the genome of fission yeast (Schizosaccharomyces pombe), which contains the smallest number of protein-coding genes yet recorded for a eukaryote: 4,824. The centromeres are between...
2.
Hayles J, Nurse P
Nat Rev Mol Cell Biol
. 2001 Sep;
2(9):647-56.
PMID: 11533722
The fission yeast, Schizosaccharomyces pombe, has been used as a model eukaryote to study processes such as the cell cycle and cell morphology. In this single-celled organism, growing in a...
3.
Behrens R, Hayles J, Nurse P
Nucleic Acids Res
. 2000 Nov;
28(23):4709-16.
PMID: 11095681
Target site selection of transposable elements is usually not random but involves some specificity for a DNA sequence or a DNA binding host factor. We have investigated the target site...
4.
Browning H, Hayles J, Mata J, Aveline L, Nurse P, McIntosh J
J Cell Biol
. 2000 Oct;
151(1):15-28.
PMID: 11018050
Cytoplasmic microtubules are critical for establishing and maintaining cell shape and polarity. Our investigations of kinesin-like proteins (klps) and morphological mutants in the fission yeast Schizosaccharomyces pombe have identified a...
5.
Porceddu A, De Veylder L, Hayles J, Van Montagu M, Inze D, Mironov V, et al.
FEBS Lett
. 1999 Apr;
446(1):182-8.
PMID: 10100639
We have analyzed five mutant alleles of two cyclin-dependent kinases from Arabidopsis thaliana, CDC2aAt and CDC2bAt, in Schizosaccharomyces pombe. Two of the five mutant alleles produced similar phenotypes for both...
6.
Hayles J, Nurse P
EMBO J
. 1995 Jun;
14(12):2760-71.
PMID: 7796804
We have monitored the tyrosine (Y15) phosphorylated and dephosphorylated forms of p34cdc2 from Schizosaccharomyces pombe as cells proceed through the cell cycle. Y15 is dephosphorylated in G1 before start and...
7.
Hayles J, Fisher D, Woollard A, Nurse P
Cell
. 1994 Sep;
78(5):813-22.
PMID: 8087848
We show here that the state of the p34cdc2-p56cdc13 mitotic B cyclin complex determines whether a fission yeast cell undergoes S phase or mitosis. Mutants defective for p56cdc13 reset to...
8.
Ayscough K, Hayles J, MacNeill S, Nurse P
Mol Gen Genet
. 1992 Apr;
232(3):344-50.
PMID: 1316996
The p34cdc2 protein kinase plays a central role in the regulation of the eukaryotic cell cycle, being required both in late G1 for the commitment to S-phase and in late...
9.
10.
Hayles J, Nurse P
Exp Cell Res
. 1989 Oct;
184(2):273-86.
PMID: 2680532
Mitosis and cell division are the final events of the cell cycle, resulting in the precise segregation of chromosomes into two daughter cells. A highly controlled and accurate segregation of...