J H Schulte
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Explore the profile of J H Schulte including associated specialties, affiliations and a list of published articles.
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26
Citations
539
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Recent Articles
1.
Althoff K, Beckers A, Bell E, Nortmeyer M, Thor T, Sprussel A, et al.
Oncogene
. 2014 Sep;
34(26):3357-68.
PMID: 25174395
Neuroblastoma, a childhood cancer that originates from neural crest-derived cells, is the most common deadly solid tumor of infancy. Amplification of the MYCN oncogene, which occurs in approximately 20-25% of...
2.
Schulte J, Schulte S, Heukamp L, Astrahantseff K, Stephan H, Fischer M, et al.
Klin Padiatr
. 2013 Oct;
225(6):303-8.
PMID: 24166094
Treatment for neuroblastoma, the most common extracranial childhood tumor, spans a broad range of aggressiveness that mirrors the risk profiles of disease subtypes, with high-risk neuroblastoma still presenting a clinical...
3.
Schramm A, Schowe B, Fielitz K, Heilmann M, Martin M, Marschall T, et al.
Br J Cancer
. 2012 Oct;
107(8):1409-17.
PMID: 23047593
Background: Using mRNA expression-derived signatures as predictors of individual patient outcome has been a goal ever since the introduction of microarrays. Here, we addressed whether analyses of tumour mRNA at...
4.
Das S, Bryan K, Buckley P, Piskareva O, Bray I, Foley N, et al.
Oncogene
. 2012 Jul;
32(24):2927-36.
PMID: 22797059
MicroRNAs (miRNAs) contribute to the pathogenesis of many forms of cancer, including the pediatric cancer neuroblastoma, but the underlying mechanisms leading to altered miRNA expression are often unknown. Here, a...
5.
Sprussel A, Schulte J, Weber S, Necke M, Handschke K, Thor T, et al.
Leukemia
. 2012 Jun;
26(9):2039-51.
PMID: 22699452
Lysine (K)-specific demethylase 1A (LSD1/KDM1A) has been identified as a potential therapeutic target in solid cancers and more recently in acute myeloid leukemia. However, the potential side effects of a...
6.
Schulte J, Lindner S, Bohrer A, Maurer J, De Preter K, Lefever S, et al.
Oncogene
. 2012 Apr;
32(8):1059-65.
PMID: 22484425
Neuroblastoma is an embryonal tumor with a heterogeneous clinical course. The tumor is presumed to be derived from the neural crest, but the cells of origin remain to be determined....
7.
Santo E, Ebus M, Koster J, Schulte J, Lakeman A, van Sluis P, et al.
Oncogene
. 2011 Aug;
31(12):1571-81.
PMID: 21860421
Neuroblastoma tumors frequently show loss of heterozygosity of chromosome 11q with a shortest region of overlap in the 11q23 region. These deletions are thought to cause inactivation of tumor suppressor...
8.
Mestdagh P, Fredlund E, Pattyn F, Schulte J, Muth D, Vermeulen J, et al.
Oncogene
. 2009 Dec;
29(9):1394-404.
PMID: 19946337
Increased activity of MYC protein-family members is a common feature in many cancers. Using neuroblastoma as a tumor model, we established a microRNA (miRNA) signature for activated MYCN/c-MYC signaling in...
9.
Cimmino F, Schulte J, Zollo M, Koster J, Versteeg R, Iolascon A, et al.
Oncogene
. 2009 Apr;
28(19):2015-23.
PMID: 19363525
Expression of Trk receptors is an important prognostic factor in neuroblastoma (NB) and other cancers. TrkB and its ligand brain-derived neurotrophic factor (BDNF) are preferentially expressed in NB with poor...
10.
Friedrichs N, Kuchler J, Endl E, Koch A, Czerwitzki J, Wurst P, et al.
J Pathol
. 2008 Oct;
216(4):428-39.
PMID: 18855347
Synovial sarcomas account for 5-10% of all soft tissue sarcomas and the majority of synovial sarcomas display characteristic t(X;18) translocations that result in enhanced transcription of the insulin-like growth factor-2...