J H Kordower
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Explore the profile of J H Kordower including associated specialties, affiliations and a list of published articles.
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144
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3574
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Recent Articles
1.
Choi S, Tittle T, Barot R, Betts D, Gallagher J, Kordower J, et al.
bioRxiv
. 2024 Sep;
PMID: 39345456
Introduction: Primary synucleinopathies, such as Parkinson's disease (PD), Dementia with Lewy bodies (DLB), and multiple system atrophy (MSA), are neurodegenerative disorders with some shared clinical and pathological features. Aggregates of...
2.
Choi S, Tittle T, Garcia-Prada D, Kordower J, Melki R, Killinger B
Acta Neuropathol Commun
. 2024 Jun;
12(1):84.
PMID: 38822421
Alpha-synuclein (αsyn) is an intrinsically disordered protein that aggregates in the brain in several neurodegenerative diseases collectively called synucleinopathies. Phosphorylation of αsyn at serine 129 (PSER129) was considered rare in...
3.
Choi S, Tittle T, Garcia-Prada D, Kordower J, Melki R, Killinger B
bioRxiv
. 2024 Apr;
PMID: 38645137
Alpha-synuclein (αsyn) is an intrinsically disordered protein that aggregates in the brain in several neurodegenerative diseases collectively called synucleinopathies. Phosphorylation of αsyn at serine 129 (PSER129) was considered rare in...
4.
Mattke S, Jun H, Hanson M, Chu S, Kordower J, Reiman E
J Prev Alzheimers Dis
. 2024 Feb;
11(2):303-309.
PMID: 38374736
Introduction: As treatments for secondary prevention of Alzheimer's disease (AD) are being studied, concerns about their value for money have appeared. We estimate cost-effectiveness of a hypothetical screening and prevention...
5.
Gluncic V, Moric M, Chu Y, Hanko V, Li J, Lukic I, et al.
Cereb Cortex
. 2020 Jun;
30(9):5190.
PMID: 32567651
No abstract available.
6.
Gluncic V, Moric M, Chu Y, Hanko V, Li J, Lukic I, et al.
Cereb Cortex
. 2019 Jun;
29(12):5285-5301.
PMID: 31220224
During fetal development, cerebral cortical neurons are generated in the proliferative zone along the ventricles and then migrate to their final positions. To examine the impact of in utero exposure...
7.
Obeso J, Stamelou M, Goetz C, Poewe W, Lang A, Weintraub D, et al.
Mov Disord
. 2017 Sep;
32(9):1264-1310.
PMID: 28887905
This article reviews and summarizes 200 years of Parkinson's disease. It comprises a relevant history of Dr. James Parkinson's himself and what he described accurately and what he missed from...
8.
Bartus R, Kordower J, Johnson Jr E, Brown L, Kruegel B, Chu Y, et al.
Neurobiol Dis
. 2015 Apr;
78:162-71.
PMID: 25841760
Substantial interest persists for developing neurotrophic factors to treat neurodegenerative diseases. At the same time, significant progress has been made in implementing gene therapy as a means to provide long-term...
9.
Roy A, Mondal S, Kordower J, Pahan K
Neuroscience
. 2015 Mar;
302:36-46.
PMID: 25783477
Parkinson's disease (PD) is a progressive neurodegenerative disease characterized by the loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc). Despite intense investigations, little is known about...
10.
Thompson V, Koprich J, Chen E, Kordower J, Terpstra B, Lipton J
Neurotoxicol Teratol
. 2011 Oct;
34(1):206-13.
PMID: 21978916
3,4-methylenedioxymethamphetamine (MDMA; ecstasy) binds with high affinity to the norepinephrine transporter (NET), making the noradrenergic system a potential target during fetal exposure. Recent data indicate that adult rats that had...