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J H Gillespie

Explore the profile of J H Gillespie including associated specialties, affiliations and a list of published articles. Areas
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Articles 138
Citations 1889
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Recent Articles
1.
Gillespie J
Ulster Med J . 2010 May; 1(3):191-6. PMID: 20475925
No abstract available.
2.
Gillespie J
Evolution . 2002 Jan; 55(11):2161-9. PMID: 11794777
This paper examines aspects of genetic draft, the stochastic force induced by substitutions at one locus on the dynamics of a closely linked locus. Of particular interest is the role...
3.
Gillespie J
Gene . 2001 Feb; 261(1):11-8. PMID: 11164032
Selective substitutions at one locus induce stochastic dynamics at a linked neutral locus that resemble genetic drift even when the population size is infinite. This new stochastic force, which is...
4.
Gillespie J
Genetics . 2000 Jun; 155(2):909-19. PMID: 10835409
Selected substitutions at one locus can induce stochastic dynamics that resemble genetic drift at a closely linked neutral locus. The pseudohitchhiking model is a one-locus model that approximates these effects...
5.
Gillespie J
Theor Popul Biol . 1999 May; 55(2):145-56. PMID: 10329514
The results of a computer simulation study of the role of population size in population genetical models of molecular evolution are presented. If the mutation rate and strength of selection...
6.
Gillespie J
Gene . 1998 Feb; 205(1-2):291-9. PMID: 9461403
A simulation study of the effects of linked selection on a neutral locus is described. Of six models of selection examined, four could be called variation-reducing as they lower the...
7.
Gillespie J
Genetics . 1994 Nov; 138(3):943-52. PMID: 7851786
The substitution processes for various models of deleterious alleles are examined using computer simulations and mathematical analyses. Most of the work focuses on the house-of-cards model, which is a popular...
8.
Gillespie J
Proc Natl Acad Sci U S A . 1993 Nov; 90(22):10411-2. PMID: 8248122
No abstract available.
9.
Gillespie J
Genetics . 1993 Jul; 134(3):971-81. PMID: 8349119
A computer simulation of the process of nucleotide substitutions in a finite haploid population subject to selection in a randomly fluctuating environment provides a number of unexpected results. For rapidly...
10.
Gillespie J
Science . 1991 Nov; 254(5034):1049. PMID: 17731526
No abstract available.