J H Cove
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Explore the profile of J H Cove including associated specialties, affiliations and a list of published articles.
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55
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926
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Recent Articles
1.
Ooi N, Eady E, Cove J, ONeill A
J Antimicrob Chemother
. 2016 Apr;
71(7):1841-4.
PMID: 27121399
Objectives: Tert-butyl benzoquinone (TBBQ) is the oxidation product of tert-butyl hydroquinone (TBHQ), an antimicrobial food additive with >40 years of safe use. TBBQ displays potent activity against Staphylococcus aureus biofilms...
2.
Ooi N, Eady E, Cove J, ONeill A
J Antimicrob Chemother
. 2014 Nov;
70(2):479-88.
PMID: 25368206
Objectives: To investigate the antistaphylococcal/antibiofilm activity and mode of action (MOA) of a panel of redox-active (RA) compounds with a history of human use and to provide a preliminary preclinical...
3.
CAILLON F, OConnell M, Eady E, Jenkins G, Cove J, Layton A, et al.
Br J Dermatol
. 2009 Oct;
162(2):296-303.
PMID: 19796181
Background: Acne is a common chronic inflammatory dermatosis of the pilosebaceous unit. It is characterized by seborrhoea, comedone formation and an inflammatory response consistent with defective cellular immunity to Propionibacterium...
4.
Mourelatos K, Eady E, Cunliffe W, Clark S, Cove J
Br J Dermatol
. 2007 Jan;
156(1):22-31.
PMID: 17199562
Background: It is generally accepted that the onset of sebum secretion occurs before puberty in boys and girls as a result of increasing androgen output during the adrenarche. Propionibacteria are...
5.
Coates P, Vyakrnam S, Ravenscroft J, Stables G, Cunliffe W, Leyden J, et al.
Br J Dermatol
. 2005 Nov;
153(6):1126-36.
PMID: 16307647
Background: Skin colonization by antibiotic-resistant propionibacteria is commonplace among acne patients globally. Increasing attention is now being paid to how resistance rates might be reduced to preserve the future efficacy...
6.
Kerr I, Reynolds E, Cove J
Biochem Soc Trans
. 2005 Oct;
33(Pt 5):1000-2.
PMID: 16246031
The precise mechanism of antibiotic-resistance-conferring ABC (ATP-binding-cassette) proteins (termed NBD2) remains open to debate. Currently, two hypotheses are recognized. In one, the NBD2 proteins are envisaged to act at the...
7.
Ravenscroft J, Layton A, Eady E, Murtagh M, Coates P, Walker M, et al.
Br J Dermatol
. 2003 Jun;
148(5):1010-7.
PMID: 12786834
Background: Staphylococcus aureus has a role in the pathophysiology of atopic eczema. Topical fusidic acid is widely used in its treatment. There is concern that topical use of fusidic acid...
8.
Cytolysin gene expression in Enterococcus faecalis is regulated in response to aerobiosis conditions
Day A, Cove J, Phillips-Jones M
Mol Genet Genomics
. 2003 Apr;
269(1):31-9.
PMID: 12715151
Here we investigate the expression of cylL(L)and cylL(S), the genes that encode the structural subunits of the cytolysin/haemolysin of Enterococcus faecalis, in response to aerobiosis conditions. Haemolysis assays of E....
9.
Ross J, Snelling A, Carnegie E, Coates P, Cunliffe W, Bettoli V, et al.
Br J Dermatol
. 2003 Mar;
148(3):467-78.
PMID: 12653738
Background: Propionibacterium acnes and P. granulosum are widely regarded as the aetiological agents of inflammatory acne. Their proliferation and metabolism are controlled using lengthy courses of oral and/or topical antibiotics....
10.
Coates P, Vyakrnam S, Eady E, Jones C, Cove J, Cunliffe W
Br J Dermatol
. 2002 May;
146(5):840-8.
PMID: 12000382
Background: Cutaneous propionibacteria are implicated in acne pathogenesis, although their exact role in the genesis of inflammation is still poorly understood. Agents, including antibiotics, that reduce the numbers of propionibacteria...