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J Goranson

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Recent Articles
1.
Goranson J, Zhu L, Sawa T, Wiener-Kronish J, Fleiszig S, Wu C, et al.
Mol Microbiol . 1997 Aug; 25(3):547-57. PMID: 9302017
The production of exoenzyme S is correlated with the ability of Pseudomonas aeruginosa to disseminate from epithelial colonization sites and cause a fatal sepsis in burn injury and acute lung...
2.
Glucksmann M, Lehto M, Tayber O, Scotti S, Berkemeier L, Pulido J, et al.
Diabetes . 1997 Jun; 46(6):1081-6. PMID: 9166684
Maturity-onset diabetes of the young 3 (MODY3) is a type of NIDDM caused by mutations in the transcription factor hepatocyte nuclear factor-1alpha (HNF-1alpha) located on chromosome 12q. We have identified...
3.
Goranson J, Hovey A, Frank D
J Bacteriol . 1997 Mar; 179(5):1646-54. PMID: 9045825
Expression of ExsC, ExsB, and ExsA (the exoenzyme S trans-regulatory locus) of Pseudomonas aeruginosa was analyzed by using complementation, RNase protection, translational fusion, and T7-directed protein expression analyses. T7 expression...
4.
Yahr T, Goranson J, Frank D
Mol Microbiol . 1996 Dec; 22(5):991-1003. PMID: 8971719
Exoenzyme S is an extracellular ADP-ribosyltransferase of Pseudomonas aeruginosa. Transposon mutagenesis of P. aeruginosa 388 was used to identify genes required for exoenzyme S production. Five Tn5Tc insertion mutants were...
5.
Goranson J, Frank D
FEMS Microbiol Lett . 1996 Jan; 135(2-3):149-55. PMID: 8595851
The dissemination of Pseudomonas aeruginosa to the bloodstream increases the likelihood of developing fatal sepsis. In experimental models, the ability to disseminate is linked to expression of the exoenzyme S...
6.
Rutz J, Liu J, Lyons J, Goranson J, Armstrong S, McIntosh M, et al.
Science . 1992 Oct; 258(5081):471-5. PMID: 1411544
The ferric enterobactin receptor (FepA) is a high-affinity ligand-specific transport protein in the outer membrane of Gram-negative bacteria. Deletion of the cell-surface ligand-binding peptides of FepA generated mutant proteins that...