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J Georges Youssef

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Citations 84
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Recent Articles
1.
Huang H, Schechtman K, Askar M, Bernadt C, Mitter B, Dore P, et al.
Transplantation . 2023 Oct; 108(3):777-786. PMID: 37899481
Background: Chronic lung allograft dysfunction (CLAD) is the leading cause of death beyond the first year after lung transplantation. The development of donor-specific antibodies (DSA) is a recognized risk factor...
2.
Brown S, Barkauskas C, Grund B, Sharma S, Phillips A, Leither L, et al.
Lancet Respir Med . 2023 Jun; 11(9):791-803. PMID: 37348524
Background: There is a clinical need for therapeutics for COVID-19 patients with acute hypoxemic respiratory failure whose 60-day mortality remains at 30-50%. Aviptadil, a lung-protective neuropeptide, and remdesivir, a nucleotide...
3.
Chan E, Goodarzi A, Sinha N, Nguyen D, Youssef J, Suarez E, et al.
Ann Thorac Surg . 2018 Feb; 105(3):893-900. PMID: 29394994
Background: Lung disease is the leading cause of morbidity and death in scleroderma patients, but scleroderma is often considered a contraindication to lung transplantation because of concerns for worse outcomes....
4.
Iacono A, Johnson B, Grgurich W, Youssef J, Corcoran T, Seiler D, et al.
N Engl J Med . 2006 Jan; 354(2):141-50. PMID: 16407509
Background: Conventional regimens of immunosuppressive drugs often do not prevent chronic rejection after lung transplantation. Topical delivery of cyclosporine in addition to conventional systemic immunosuppression might help prevent acute and...
5.
Dickman K, Youssef J, Mathew S, Said S
Am J Respir Cell Mol Biol . 2003 Jul; 30(2):139-44. PMID: 12855408
We earlier showed that the ionotropic glutamate receptor agonist N-methyl D-aspartate (NMDA) induces excitotoxic pulmonary edema, and that endogenous activation of NMDA receptors (NMDAR) could mediate lung injury caused by...