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J G Naglich

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Recent Articles
1.
Naglich J, Gupta E, Fargnoli J, Henderson A, Lewin A, Talbott R, et al.
Cancer Res . 2001 Dec; 61(23):8480-5. PMID: 11731431
BMS-275291 is an p.o. bioavailable, sulfhydryl-based matrix metalloproteinase (MMP) inhibitor currently in clinical development for the treatment of cancer. This inhibitor was designed to potently inhibit MMP activities while minimally...
2.
Blankenship C, Naglich J, Whaley J, Seizinger B, Kley N
Oncogene . 1999 Apr; 18(8):1529-35. PMID: 10102622
The VHL tumor suppressor gene has previously been reported to encode a protein of 213 amino acid residues. Here we report the identification of a second major VHL gene product...
3.
Gao J, Naglich J, Laidlaw J, Whaley J, Seizinger B, Kley N
Cancer Res . 1995 Feb; 55(4):743-7. PMID: 7850784
The human von Hippel-Lindau disease (VHL) gene has recently been identified and, based on the nucleotide sequence of a partial cDNA clone, has been predicted to encode a novel protein...
4.
Brown J, Almond B, Naglich J, Eidels L
Proc Natl Acad Sci U S A . 1993 Sep; 90(17):8184-8. PMID: 8367482
DTS-II is a highly diphtheria toxin (DT)-sensitive cell line previously isolated by transfection of wild-type DT-resistant mouse L-M(TK-) cells with the cDNA encoding a monkey Vero cell DT receptor. DTS-II...
5.
Naglich J, Metherall J, Russell D, Eidels L
Cell . 1992 Jun; 69(6):1051-61. PMID: 1606612
A monkey cDNA (pDTS) encoding a diphtheria toxin (DT) sensitivity determinant was isolated by expression cloning in mouse L-M cells. Mouse cells are naturally resistant to DT, because they lack...
6.
Naglich J, Rolf J, Eidels L
Proc Natl Acad Sci U S A . 1992 Mar; 89(6):2170-4. PMID: 1549577
Diphtheria toxin (DT), a bacterial protein exotoxin, inactivates mammalian cell elongation factor 2 after toxin internalization by receptor-mediated endocytosis. To isolate the DT receptor, we cotransfected DT-resistant wild-type mouse L-M...
7.
Naglich J, Eidels L
Proc Natl Acad Sci U S A . 1990 Sep; 87(18):7250-4. PMID: 2402506
Diphtheria toxin (DTX)-sensitive mouse cells were isolated from a toxin-resistant thymidine kinase (TK)-negative L-M(TK-) mouse cell population that was transfected with DNA from highly toxin-sensitive monkey Vero cells. Sensitivity to...
8.
Naglich J, Andrews Jr R
Plasmid . 1988 Sep; 20(2):113-26. PMID: 2853391
The Staphylococcus aureus plasmids pC194 and pUB110 were introduced into Bacillus thuringiensis subsp. israelensis by using the Streptococcus faecalis transposon Tn916 as a mobilizing agent. Plasmid transfer occurred only when...
9.
Naglich J, Andrews Jr R
Plasmid . 1988 Mar; 19(2):84-93. PMID: 2901772
The conjugative Streptococcus faecalis transposon Tn916 was introduced into Bacillus thuringiensis subsp. israelensis by filter matings with S. faecalis. B. thuringiensis transconjugants resistant to tetracycline (Tetr) were detected at a...
10.
Holder I, Naglich J
J Trauma . 1986 Feb; 26(2):118-22. PMID: 2418208
Flagella preparations of the two antigenic types that make up all the flagella antigens in Pseudomonas aeruginosa were used, individually, to immunize mice. Mice thus immunized were protected when burned...