J F Powers
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Explore the profile of J F Powers including associated specialties, affiliations and a list of published articles.
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31
Citations
236
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Recent Articles
1.
Powers J, Picard K, Tischler A
Horm Metab Res
. 2009 Jun;
41(9):710-4.
PMID: 19551609
Receptor tyrosine kinase RET is normally expressed at low levels in chromaffin cells and high levels in sympathetic neurons. Paradoxically, it is overexpressed in subsets of pheochromocytomas. The overexpressed protein...
2.
Powers J, Evinger M, Zhi J, Picard K, Tischler A
Neuroscience
. 2007 Jun;
147(4):928-37.
PMID: 17582688
Pheochromocytomas are adrenal medullary tumors that typically occur in adult patients, with increased frequency in multiple endocrine neoplasia type 2, von Hippel-Lindau disease, familial paraganglioma syndromes and neurofibromatosis type 1...
3.
Powers J, Brachold J, Ehsani S, Tischler A
Neuroscience
. 2005 Apr;
132(3):605-12.
PMID: 15837122
The receptor tyrosine kinase, ret, is activated by glial cell line-derived neurotrophic factor, neurturin and related ligands that bind to glycosylphosphatidylinositol-tailed receptors GFRalpha1-4. Ret expression is developmentally regulated and detectable...
4.
Tischler A, Powers J, Alroy J
Histol Histopathol
. 2004 May;
19(3):883-95.
PMID: 15168351
Pheochromocytomas are neuroendocrine tumors of adrenal chromaffin cells. They are rare in all species except rats but occur with increased frequency in several human familial tumor syndromes. Concurrence of pheochromocytoma...
5.
Powers J, Brachold J, Schelling K, Tischler A
Neurosci Lett
. 2004 Jan;
356(1):5-8.
PMID: 14746888
The immunosuppressive drugs FK506 and cyclosporin inhibit T- and B-lymphocyte proliferation and exert neuritogenic and/or cytoprotective effects on several types of neurons. While the immunosuppressive actions of both drugs are...
6.
Powers J, Schelling K, Tischler A
Neuroscience
. 2001 Dec;
108(2):341-9.
PMID: 11734366
Neurturin and glial cell line-derived neurotrophic factor are novel mitogens for normal adult rat chromaffin cells in vitro. These neurotrophic factors differ from the previously described adult chromaffin cell mitogens,...
7.
Powers J, Misra S, Schelling K, Varticovski L, Tischler A
J Cell Biochem Suppl
. 2001 Jul;
Suppl 36:89-98.
PMID: 11455574
Increase of intracellular cyclic adenosine monophosphate by the permeant cyclic adenosine monophosphate analog, 8-(4-chlorophenylthio)-adenosine 3':5'- cyclic monophosphate, is mitogenic for normal adult rat chromaffin cells. The mitogenic effect is blocked...
8.
Powers J, Evinger M, Tsokas P, Bedri S, Alroy J, Shahsavari M, et al.
Cell Tissue Res
. 2001 Jan;
302(3):309-20.
PMID: 11151443
Transplantable tumors and cell lines have been developed from pheochromocytomas arising in mice with a heterozygous knockout mutation of the neurofibromatosis gene, Nf1. Nf1 encodes a ras-GTPase-activating protein, neurofibromin, and...
9.
Smith-Hicks C, Sizer K, Powers J, Tischler A, Costantini F
EMBO J
. 2000 Feb;
19(4):612-22.
PMID: 10675330
Dominantly inherited multiple endocrine neoplasia type 2B (MEN2B) is characterized by tumors of the thyroid C-cells and adrenal chromaffin cells, together with ganglioneuromas of the gastrointestinal tract and other developmental...
10.
Tischler A, Powers J, Pignatello M, Tsokas P, Downing J, McClain R
Toxicol Sci
. 1999 Sep;
51(1):9-18.
PMID: 10496673
Adrenal medullary hyperplasia and pheochromocytomas are induced in rats by a variety of non-genotoxic agents, and we have hypothesized that these agents induce lesions indirectly by stimulating chromaffin cell proliferation....