J E Moore Jr
Overview
Explore the profile of J E Moore Jr including associated specialties, affiliations and a list of published articles.
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36
Citations
636
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Recent Articles
1.
Quantification of the Whole Lymph Node Vasculature Based on Tomography of the Vessel Corrosion Casts
Jafarnejad M, Ismail A, Duarte D, Vyas C, Ghahramani A, Zawieja D, et al.
Sci Rep
. 2019 Sep;
9(1):13380.
PMID: 31527597
Lymph nodes (LN) are crucial for immune function, and comprise an important interface between the blood and lymphatic systems. Blood vessels (BV) in LN are highly specialized, featuring high endothelial...
2.
Bertram C, Macaskill C, Davis M, Moore Jr J
Biomech Model Mechanobiol
. 2018 Jun;
17(5):1513-1532.
PMID: 29948540
The paper describes the extension of a previously developed model of pressure-dependent contraction rate to the case of multiple lymphangions. Mechanical factors are key modulators of active lymphatic pumping. As...
3.
Bertram C, Macaskill C, Davis M, Moore Jr J
Biomech Model Mechanobiol
. 2017 Jul;
16(6):1987-2003.
PMID: 28699120
Lymph is transported along collecting lymphatic vessels by intrinsic and extrinsic pumping. The walls have muscle of a type intermediate between blood-vascular smooth muscle and myocardium; a contracting segment between...
4.
Bertram C, Macaskill C, Moore Jr J
Med Eng Phys
. 2016 May;
38(7):656-663.
PMID: 27185045
The transport capacity of a contractile segment of lymphatic vessel is defined by its pump function curve relating mean flow-rate and adverse pressure difference. Numerous system characteristics affect curve shape...
5.
Jafarnejad M, Woodruff M, Zawieja D, Carroll M, Moore Jr J
Lymphat Res Biol
. 2015 Dec;
13(4):234-47.
PMID: 26683026
Background: Lymph nodes (LNs) are positioned strategically throughout the body as critical mediators of lymph filtration and immune response. Lymph carries cytokines, antigens, and cells to the downstream LNs, and...
6.
Jafarnejad M, Cromer W, Kaunas R, Zhang S, Zawieja D, Moore Jr J
Am J Physiol Heart Circ Physiol
. 2015 Jan;
308(7):H697-706.
PMID: 25617358
The shear stress applied to lymphatic endothelial cells (LEC) by lymph flow changes dramatically under normal conditions as well as in response to disease conditions and immune reactions. In general,...
7.
Richardson W, van der Voort D, Wilson E, Moore Jr J
Mol Cell Biomech
. 2014 Jan;
10(3):245-65.
PMID: 24396979
Non-uniform stress and strain fields are prevalent in many tissues in vivo, and often exacerbated by disease or injury. These mechanical gradients potentially play a role in contributing to pathological...
8.
Bertram C, Macaskill C, Davis M, Moore Jr J
Biomech Model Mechanobiol
. 2013 Jun;
13(2):401-16.
PMID: 23801424
Our published model of a lymphatic vessel consisting of multiple actively contracting segments between non-return valves has been further developed by the incorporation of properties derived from observations and measurements...
9.
Richardson W, Wilson E, Moore Jr J
Am J Physiol Cell Physiol
. 2013 May;
305(1):C100-10.
PMID: 23657569
Disease-related phenotype modulation of many cell types has been shown to be closely related to mechanical loading conditions; for example, vascular smooth muscle cell (SMC) phenotype shift from a mature,...
10.
Bertram C, Macaskill C, Moore Jr J
Comput Methods Biomech Biomed Engin
. 2013 Feb;
17(14):1519-34.
PMID: 23387996
An existing lumped-parameter model of multiple lymphangions (lymphatic vascular segments) in series is adapted for the incorporation of recent physiological measurements of lymphatic vascular properties. The new data show very...