J E Michaels
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Explore the profile of J E Michaels including associated specialties, affiliations and a list of published articles.
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22
Citations
80
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Recent Articles
1.
Michaels J, Shiba K, Miller W
Biochim Biophys Acta
. 1999 Aug;
1433(1-2):103-9.
PMID: 10446363
We previously reported that C-terminal fragments of Escherichia coli Ile-tRNA synthetase, a monomeric enzyme of 939 amino acids, act as dominant negative inhibitors of the wild-type enzyme in vivo and...
2.
Michaels J, Cardell R
Anat Rec
. 1997 Jul;
248(3):406-12.
PMID: 9214558
Background: The intralobular distribution of activity of glycogen phosphorylase (GP), a key enzyme in the breakdown of glycogen, was evaluated to determine changes during early glycogen synthesis. Hepatic GP activity...
3.
Michaels J, Schimmel P, Shiba K, Miller W
Proc Natl Acad Sci U S A
. 1996 Dec;
93(25):14452-5.
PMID: 8962072
Dominant negative inhibition is most commonly seen when a mutant subunit of a multisubunit protein is coexpressed with the wild-type protein so that assembly of a functional oligomer is impaired....
4.
Michaels J, CARDELL Jr R
Anat Rec
. 1993 Jul;
236(3):486-92.
PMID: 8363053
Hepatic glycogen synthase activity was localized in normal and adrenalectomized (ADX) rats after fasting overnight and in fasted ADX rats after injection of dexamethasone (DEX) 2-8 h prior to sacrifice...
5.
Pruchno R, Michaels J, Potashnik S
J Gerontol
. 1990 Nov;
45(6):S259-66.
PMID: 2229952
A theoretical model predicting "desire to institutionalize" and actual institutionalization was developed and tested on a sample of 220 persons caring for a demented spouse. Significant predictors of "desire to...
6.
Pruchno R, KLEBAN M, Michaels J, Dempsey N
J Gerontol
. 1990 Sep;
45(5):P192-9.
PMID: 2394915
This study modeled the causal relationship between physical health and depression among a sample of 315 people providing home care for a spouse who had been diagnosed as having Alzheimer's...
7.
Michaels J, Garfield S, Hung J, CARDELL Jr R
Am J Anat
. 1990 Aug;
188(4):419-28.
PMID: 2392998
The effects of short- and long-term stimulation of glycogen synthesis elicited by dexamethasone were studied by light (LM) and electron (EM) microscopic radioautography (RAG) and biochemical analysis. Adrenalectomized rats were...
8.
Michaels J, Garfield S, Hung J, CARDELL Jr R
Anat Rec
. 1989 May;
224(1):22-8.
PMID: 2786354
Labeling of hepatic glycogen derived from 3H-galactose and 3H-glucose was compared shortly after intravenous injection in control-fed rats. The rats were allowed to accumulate 5-8% glycogen prior to receiving label....
9.
CARDELL Jr R, Michaels J, Hung J, Cardell E
J Cell Biol
. 1985 Jul;
101(1):201-6.
PMID: 4008528
Hormonal control of hepatic glycogen and blood glucose levels is one of the major homeostatic mechanisms in mammals: glycogen is synthesized when portal glucose concentration is sufficiently elevated and degraded...
10.
Michaels J, Hung J, Garfield S, CARDELL Jr R
Am J Anat
. 1984 May;
170(1):23-37.
PMID: 6731338
Very low hepatic glycogen levels are achieved by overnight fasting of adrenalectomized (ADX) rats. Subsequent injection of dexamethasone (DEX), a synthetic glucocorticoid, stimulates marked increases in glycogen synthesis. Using this...