J E Bottenstein
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Explore the profile of J E Bottenstein including associated specialties, affiliations and a list of published articles.
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17
Citations
691
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Recent Articles
1.
Michler-Stuke A, Wolff J, Bottenstein J
Int J Dev Neurosci
. 2014 May;
2(6):575-84.
PMID: 24874398
A previously described serum-free, defined medium (G2 medium) containing transferrin, selenium, hydrocortisone, biotin, fibroblast growth factor (FGF) and fibronectin developed for the growth of human and rat derived glioma cells...
2.
Zompa E, Moyer M, Cain L, Bottenstein J, Hulsebosch C
Transplantation
. 1998 Nov;
66(7):928-31.
PMID: 9798706
Xenografts, specifically transplantation of human cells into other species, are a valuable tool in preclinical transplantation experiments. A central issue is accurate identification of the grafted cells, particularly in cases...
3.
HUNTER S, Bottenstein J
J Neurosci Res
. 1991 Apr;
28(4):574-82.
PMID: 1870158
During development, myelin-forming oligodendrocytes and type 2 astrocytes are believed to arise from bipotential (O-2A) glial progenitors. Previously we found that conditioned medium (CM) from the B104 rat CNS neuronal...
4.
HUNTER S, Bottenstein J
Brain Res Dev Brain Res
. 1990 Jul;
54(2):235-48.
PMID: 2397589
Responses of oligodendrocyte/type 2 astrocyte (O-2A) glial progenitors from neonatal rat brains to different growth factors were studied by a new, serum-free method. Enriched tertiary cultures of O-2A progenitors were...
5.
HUNTER S, Bottenstein J
Brain Res Dev Brain Res
. 1989 Sep;
49(1):33-49.
PMID: 2791266
The growth-promoting activity of conditioned medium (CM) from the B104 CNS neuronal cell line was studied in glial cultures from neonatal rat brain. This CM at 33% (v/v; 8-12 micrograms...
6.
Bottenstein J, HUNTER S, Seidel M
J Neurosci Res
. 1988 Jul;
20(3):291-303.
PMID: 2852260
Recent studies suggest that heterotypic cell-cell interactions influence gliogenesis in the developing rat central nervous system. CNS neuron-derived factors have been hypothesized to exist, and several have been identified and...
7.
8.
Norton W, Farooq M, Chiu F, Bottenstein J
Glia
. 1988 Jan;
1(6):403-14.
PMID: 2976400
Enriched preparations of oligodendrocytes, isolated either from adult bovine brain or from 30-day-old rat brain, eventually yield cultures in MEM-15% calf serum that contain, in addition to oligodendrocytes, proliferating astrocytes...
9.
Bottenstein J
Proc Natl Acad Sci U S A
. 1986 Mar;
83(6):1955-9.
PMID: 3456614
I have defined the basic requirements for the proliferation of cell lines expressing oligodendrocyte properties and for the survival of galactocerebroside-positive oligodendrocytes derived from neonatal rat brains. Conventional serum-containing medium...
10.
Michler-Stuke A, Bottenstein J
J Neurosci Res
. 1982 Jan;
7(2):215-28.
PMID: 6212693
A serum-free defined medium has been formulated that supports proliferation and morphologic differentiation of U-251 MGsp human and C6-2BD rat glioma cells. This defined medium consists of a basal medium...