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J D Vickers

Explore the profile of J D Vickers including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Vickers J, Kinlough-Rathbone R, Packham M, Mustard J
Platelets . 2010 Nov; 1(4):199-204. PMID: 21043948
Platelet phosphoinositide metabolism was examined during platelet-fibrin clot formation stimulated by ADP (10 μM) plus reptilase, or by thrombin (1 U/ml), for 120 s in the presence of fibrinogen, to...
2.
Vickers J, Kinlough-Rathbone R, Packham M
Platelets . 2010 Nov; 3(4):201-9. PMID: 21043879
Phosphoinositide metabolism in rabbit platelets prelabelled with [(32)P]phosphate and [(3)H]inositol was stimulated by platelet activating factor (PAF, 1-0-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine) with stirring at 200 rpm for 120 s in the presence of...
3.
Vickers J
Platelets . 2006 Jun; 10(4):228-37. PMID: 16801097
Incubation of polymerizing fibrin with washed, chymotrypsin-treated (CT) rabbit platelets resulted in the formation of platelet-fibrin clots, a decrease of 27.4% (P < 0.001, n = 20) in the amount...
4.
Vickers J
Platelets . 2006 Jun; 9(6):390-4. PMID: 16793723
Binding of ligands, including RGD-containing peptides, to the platelet fibrinogen receptor, integrin alphaIIb beta3 has been reported to cause outside-in signals, which result in clustering of occupied receptors and changes...
5.
Vickers J, Packham M, Kinlough-Rathbone R
Am J Hematol . 1997 Apr; 54(4):288-95. PMID: 9092683
The formation of inositol phosphates was compared in aspirin-treated, washed human platelets suspended in Tyrode's-albumin solution containing 2 mM calcium and stimulated with SFLLRN (thrombin receptor-activating peptide) or thrombin. SFLLRN...
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Vickers J, Packham M, Kinlough-Rathbone R
Ann N Y Acad Sci . 1994 Apr; 714:287-90. PMID: 8017781
No abstract available.
8.
Vickers J, Perry D
Thromb Haemost . 1993 Nov; 70(5):807-11. PMID: 8128438
We have examined in unstimulated and thrombin-stimulated human and rabbit platelets the localization and behavior of aequorin loaded by a variety of published methods. When platelets were suspended at 37...
9.
Vickers J
J Pharmacol Exp Ther . 1993 Sep; 266(3):1156-63. PMID: 8396627
The effect of the putative phospholipase C inhibitor U73122 (1-[6-[[17 beta-3-methoxyestra-1,3,5(10)trien-17-yl]amino]hexyl]-1H- pyrrole-2,5-dione) on platelet phosphoinositide metabolism was examined. In unstimulated rabbit platelets prelabeled with [32P]phosphate and [3H]glycerol, U73122 caused decreases...
10.
Vickers J
Eur J Biochem . 1993 Aug; 216(1):231-7. PMID: 8396029
ADP-stimulation of washed human platelets suspended in Tyrode/albumin solution containing Ca2+ (2 mM) and fibrinogen (0.4 mg/ml) causes extensive, reversible aggregation without appreciable secretion of granule contents. Under these conditions...