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J D Roache

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Articles 52
Citations 487
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Recent Articles
1.
Casada J, Roache J
Int J Psychophysiol . 2006 Jul; 62(2):243-8. PMID: 16814888
We have previously reported that subjects with posttraumatic stress disorder (PTSD) differ from trauma controls in their ability to produce and withhold responses in the Stop-Signal Task depending on the...
2.
Gomez T, Roache J, Meisch R
Psychopharmacology (Berl) . 2002 Apr; 161(1):86-94. PMID: 11967635
Rationale: Benzodiazepines are among the most frequently prescribed drugs and are usually taken by mouth. However, there have been few studies of oral self-administration of these drugs, and the results...
3.
Johnson B, Javors M, Roache J, Zanca N
Alcohol Clin Exp Res . 2001 Jun; 25(6):847-9. PMID: 11410720
Background: Recently, we showed by using self-report that combining ondansetron (4 microg/kg twice a day) and naltrexone (25 mg twice a day) was effective at reducing drinking and increasing abstinence...
4.
Johnson B, Roache J, Javors M, DiClemente C, Cloninger C, Prihoda T, et al.
JAMA . 2000 Aug; 284(8):963-71. PMID: 10944641
Context: Early-onset alcoholism differs from late-onset alcoholism by its association with greater serotonergic abnormality and antisocial behaviors. Thus, individuals with early-onset alcoholism may be responsive to treatment with a selective...
5.
Johnson B, Cloninger C, Roache J, Bordnick P, Ruiz P
Am J Addict . 2000 Jul; 9(1):17-27. PMID: 10914290
Subtyping alcoholics may provide a more accurate guide as to the course and character of the disease. Classifications of different ages of onset of problem drinking have so far resulted...
6.
HARRIS J, Roache J, Thornton J
Alcohol Alcohol . 2000 Jul; 35(4):319-23. PMID: 10905994
In the human central nervous system, the gamma-aminobutyric acid (GABA) type A receptor complex undergoes changes with both acute and chronic exposure to sedative-hypnotic drugs. These changes contribute to both...
7.
Roache J, Grabowski J, Schmitz J, CRESON D, Rhoades H
J Clin Psychopharmacol . 2000 Feb; 20(1):61-8. PMID: 10653210
Two experiments examined the effects of methylphenidate in male and female patients enrolled in an outpatient treatment program for primary cocaine dependence. The first study was a component of a...
8.
Oswald L, Roache J, Rhoades H
Exp Clin Psychopharmacol . 1999 Dec; 7(4):379-90. PMID: 10609973
Twenty-seven patients with generalized anxiety or panic disorder participated in a 6-week outpatient study. Participants received capsules containing either alprazolam or placebo and were free to choose between them for...
9.
Johnson B, Roache J, Bordnick P
Psychopharmacology (Berl) . 1999 Aug; 144(3):295-300. PMID: 10435398
Rationale: Dopamine (DA) pathways in the midbrain mediate d-methamphetamine's rewarding effects associated with its abuse liability. Isradipine, a dihydropyridine-class calcium channel antagonist, reduces the rewarding effects of psychostimulants such as...
10.
Grabowski J, Roache J, Schmitz J, Rhoades H, Creson D, Korszun A
J Clin Psychopharmacol . 1997 Dec; 17(6):485-8. PMID: 9408812
Agonists, or "replacement medications," are useful adjuncts in treatment of opiate and nicotine dependence. They have not been systematically examined in cocaine dependence. Results of early open trials with methylphenidate...