J D Mikkelsen
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Explore the profile of J D Mikkelsen including associated specialties, affiliations and a list of published articles.
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Articles
175
Citations
2497
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Recent Articles
1.
Aripaka S, Bech-Azeddine R, Jorgensen L, Chughtai S, Gaarde C, Bendix T, et al.
Eur Spine J
. 2021 May;
30(10):2967-2974.
PMID: 34023967
Purpose: The molecular mechanism behind pain in degenerative disc disease (DDD) and chronic low back pain (LBP) patients is largely unknown. This present study examines the association of LBP and...
2.
Bortz D, Upton B, Mikkelsen J, Bruno J
Neuropharmacology
. 2016 Aug;
111:78-91.
PMID: 27569994
Positive allosteric modulators (PAMs) of α7 nicotinic acetylcholine receptors (α7nAChRs) exhibit pro-cognitive effects in animal models of schizophrenia and are targets for the discovery of cognition-enhancing drugs. However, little is...
3.
Baum A, Hansen P, Norgaard L, Sorensen J, Mikkelsen J
J Dairy Sci
. 2016 Jun;
99(8):6071-6079.
PMID: 27265175
In this study, we introduce enzymatic perturbation combined with Fourier transform infrared (FTIR) spectroscopy as a concept for quantifying casein in subcritical heated skim milk using chemometric multiway analysis. Chymosin...
4.
Salaga M, Blomster L, Piechota-Polanczyk A, Zielinska M, Jacenik D, Cygankiewicz A, et al.
J Pharmacol Exp Ther
. 2015 Oct;
356(1):157-69.
PMID: 26462538
The α7 pentamer nicotinic acetylcholine receptors (nAChRs) are a target in transduction of anti-inflammatory signals from the central nervous system to the gastrointestinal (GI) tract. The aim of this study...
5.
Menezes M, Santini M, Benvenga M, Marek G, Merchant K, Mikkelsen J, et al.
Neurosci J
. 2015 Aug;
2013:736439.
PMID: 26317098
Metabotropic glutamate 2/3 (mGlu2/3) receptors have emerged as potential therapeutic targets due to the ability of mGlu2/3 receptor agonists to modulate excitatory transmission at specific synapses. LY354740 and LY379268 are...
6.
Jorgensen A, Magnusson P, Hanson L, Kirkegaard T, Benveniste H, Lee H, et al.
Acta Psychiatr Scand
. 2015 Jul;
133(2):154-164.
PMID: 26138003
Objective: To investigate the role of hippocampal plasticity in the antidepressant effect of electroconvulsive therapy (ECT). Method: We used magnetic resonance (MR) imaging including diffusion tensor imaging (DTI) and proton...
7.
Overgaard A, Axel A, Lie M, Hansen H, Mikkelsen J
Endocr Regul
. 2015 May;
49(2):51-7.
PMID: 25960005
Objective: It is well known that reproductive capacity is lower in obese individuals, but what mediators and signals are involved is unclear. Kisspeptin is a potent stimulator of GnRH release,...
8.
Jers C, Guo Y, Kepp K, Mikkelsen J
Protein Eng Des Sel
. 2015 Jan;
28(2):37-44.
PMID: 25573534
This study aimed to improve the hydrolase activity of the well-characterised bacterial sialidase from Micromonospora viridifaciens. The enzyme and its mutated versions were produced in Bacillus subtilis and secreted to...
9.
Bartzen-Sprauer J, Klosen P, Ciofi P, Mikkelsen J, Simonneaux V
J Neuroendocrinol
. 2014 Jun;
26(8):510-20.
PMID: 24935671
In many species, sexual activity varies on a seasonal basis. Kisspeptin (Kp), a hypothalamic neuropeptide acting as a strong activator of gonadotrophin-releasing hormone neurones, plays a critical role in this...
10.
Bortz D, Jorgensen C, Mikkelsen J, Bruno J
Neuropharmacology
. 2014 Apr;
84:19-30.
PMID: 24747179
Cognitive deficits in schizophrenia (SZ) reflect maturational disruptions within a neural system that includes the ventral hippocampus (VH), nucleus accumbens (NAc), basal forebrain, and prefrontal cortex (PFC). A better understanding...