J Cools
Overview
Explore the profile of J Cools including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
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Articles
42
Citations
1157
Followers
0
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Recent Articles
1.
Degryse S, de Bock C, Demeyer S, Govaerts I, Bornschein S, Verbeke D, et al.
Leukemia
. 2018 Sep;
32(12):2731.
PMID: 30232463
Following the publication of this article the authors noted that data describing precisely where phosphorylation sites in proteins modulated following JAK1 or JAK3 inhibition in mutant T-ALL samples was not...
2.
Bornschein S, Demeyer S, Stirparo R, Gielen O, Vicente C, Geerdens E, et al.
Leukemia
. 2017 Nov;
32(4):941-951.
PMID: 29151585
T-cell acute lymphoblastic leukemia (T-ALL) is caused by the accumulation of multiple mutations combined with the ectopic expression of transcription factors in developing T cells. However, the molecular basis underlying...
3.
Degryse S, de Bock C, Demeyer S, Govaerts I, Bornschein S, Verbeke D, et al.
Leukemia
. 2017 Aug;
32(3):788-800.
PMID: 28852199
Mutations in the interleukin-7 receptor (IL7R) or the Janus kinase 3 (JAK3) kinase occur frequently in T-cell acute lymphoblastic leukemia (T-ALL) and both are able to drive cellular transformation and...
4.
Girardi T, Vereecke S, Sulima S, Khan Y, Fancello L, Briggs J, et al.
Leukemia
. 2017 Jul;
32(3):809-819.
PMID: 28744013
Several somatic ribosome defects have recently been discovered in cancer, yet their oncogenic mechanisms remain poorly understood. Here we investigated the pathogenic role of the recurrent R98S mutation in ribosomal...
5.
Vanden Bempt M, Demeyer S, Mentens N, Geerdens E, de Bock C, Wlodarska I, et al.
Leukemia
. 2016 Mar;
30(9):1913-6.
PMID: 27021554
No abstract available.
6.
Durinck K, Van Loocke W, van der Meulen J, Van de Walle I, Ongenaert M, Rondou P, et al.
Leukemia
. 2015 Jun;
29(12):2317-27.
PMID: 26108691
The TLX1 transcription factor is critically involved in the multi-step pathogenesis of T-cell acute lymphoblastic leukemia (T-ALL) and often cooperates with NOTCH1 activation during malignant T-cell transformation. However, the exact...
7.
Morscio J, Dierickx D, Ferreiro J, Herreman A, Van Loo P, Bittoun E, et al.
Am J Transplant
. 2013 Mar;
13(5):1305-16.
PMID: 23489474
Posttransplant patients are at risk of developing a potentially life-threatening posttransplantation lymphoproliferative disorder (PTLD), most often of diffuse large B cell lymphoma (DLBCL) morphology and associated with Epstein-Barr Virus (EBV)...
8.
Hoeben A, Martin D, Clement P, Cools J, Gutkind J
Int J Cancer
. 2012 Aug;
132(5):1042-50.
PMID: 22865653
The epidermal growth factor receptor (EGFR) plays an important role in the pathogenesis of head and neck squamous cell carcinoma (HNSCC). Despite the high expression of EGFR in HNSCC, EGFR...
9.
Lierman E, Smits S, Cools J, Dewaele B, Debiec-Rychter M, Vandenberghe P
Leukemia
. 2012 Feb;
26(7):1693-5.
PMID: 22301675
No abstract available.
10.
Van Vlierberghe P, Patel J, Abdel-Wahab O, Lobry C, Hedvat C, Balbin M, et al.
Leukemia
. 2010 Oct;
25(1):130-4.
PMID: 21030981
Loss of function mutations and deletions encompassing the plant homeodomain finger 6 (PHF6) gene are present in about 20% of T-cell acute lymphoblastic leukemias (ALLs). Here, we report the identification...