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J Cheung

Explore the profile of J Cheung including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 60
Citations 1273
Followers 0
Related Specialties
General Medicine
Neurology
Public Health
Top 10 Co-Authors
S Sharma
G Hampson
N Y Ip
F C Ip
I Fogelman
A K Fu
A S Wierzbicki
P J Lumb
Y T Mak
S W Scherer
Published In
Can Fam Physician
Neurosci Lett
IEEE Trans Image Process
Aust Health Rev
Mol Cell Neurosci
Affiliations
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Recent Articles
1.
Improving selection procedures in health professions education from the applicant perspective: an interview study
Fikrat-Wevers S, Stegers-Jager K, Mulder L, Cheung J, Van Den Broek W, Woltman A
BMC Med Educ . 2024 Aug; 24(1):849. PMID: 39112957
Introduction: Applicant perceptions of selection impact motivation and performance during selection, and student diversity. However, in-depth insight into which values underly these perceptions is lacking, creating challenges for aligning selection...
2.
Rational design, synthesis and testing of novel tricyclic topoisomerase inhibitors for the treatment of bacterial infections part 2
Kirk R, Ratcliffe A, Noonan G, Uosis-Martin M, Lyth D, Bardell-Cox O, et al.
RSC Med Chem . 2021 Jun; 11(12):1379-1385. PMID: 34095845
Building on our previously-reported novel tricyclic topoisomerase inhibitors (NTTIs), we disclose the discovery of REDX07965, which has an MIC of 0.5 μg mL against , favourable pharmacokinetic properties, selectivity human...
3.
Rational design, synthesis and testing of novel tricyclic topoisomerase inhibitors for the treatment of bacterial infections part 1
Kirk R, Ratcliffe A, Noonan G, Uosis-Martin M, Lyth D, Bardell-Cox O, et al.
RSC Med Chem . 2021 Jun; 11(12):1366-1378. PMID: 34095844
The alarming reduction in drug effectiveness against bacterial infections has created an urgent need for the development of new antibacterial agents that circumvent bacterial resistance mechanisms. We report here a...
4.
Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses
Blumberg L, Humphries J, Jones S, Pearce L, Holgate R, Hearn A, et al.
Sci Adv . 2020 Jan; 5(12):eaax9586. PMID: 31897428
The neonatal crystallizable fragment receptor (FcRn) functions as an intracellular protection receptor for immunoglobulin G (IgG). Recently, several clinical studies have reported the lowering of circulating monomeric IgG levels through...
5.
Exploration of Shared Genetic Architecture Between Subcortical Brain Volumes and Anorexia Nervosa
Walton E, Hibar D, Yilmaz Z, Jahanshad N, Cheung J, Batury V, et al.
Mol Neurobiol . 2018 Dec; 56(7):5146-5156. PMID: 30519816
In MRI scans of patients with anorexia nervosa (AN), reductions in brain volume are often apparent. However, it is unknown whether such brain abnormalities are influenced by genetic determinants that...
6.
Development of Multiwell-Plate Methods Using Pure Cultures of Methanogens To Identify New Inhibitors for Suppressing Ruminant Methane Emissions
Weimar M, Cheung J, Dey D, McSweeney C, Morrison M, Kobayashi Y, et al.
Appl Environ Microbiol . 2017 May; 83(15). PMID: 28526787
Hydrogenotrophic methanogens typically require strictly anaerobic culturing conditions in glass tubes with overpressures of H and CO that are both time-consuming and costly. To increase the throughput for screening chemical...
7.
SU-E-T-560: Inter- and Intra-Fraction Variations in Esophageal Dose for Lung Cancer Patients, and the Impact of Setup Technique and Treatment Modality
Carroll M, Cheung J, Zhang L, Court L
Med Phys . 2017 May; 39(6Part19):3834. PMID: 28517074
Purpose: To understand the dose-response of the esophagus in photon and proton therapy, it is important to appreciate the variations in delivered dose caused by inter- and intra-fraction motion. Methods:...
8.
Sci-Thurs PM: Delivery-12: Correction and calibration of megavoltage cone-beam CT images for the calculation of the dose of the day
Aubry J, Cheung J, Yom S, Gottschalk A, Aubin M, Morin O, et al.
Med Phys . 2017 May; 35(7Part2):3401. PMID: 28512819
Purpose: To show that accurate dose calculations can be achieved with megavoltage cone-beam CT (MVCBCT) images of head-and-neck (H&N) and prostate sites, allowing the verification of the daily dose distribution...
9.
Association of bone turnover markers and arterial stiffness in pre-dialysis chronic kidney disease (CKD)
Manghat P, Souleimanova I, Cheung J, Wierzbicki A, Harrington D, Shearer M, et al.
Bone . 2011 Feb; 48(5):1127-32. PMID: 21281749
Vascular calcification (VC) is highly prevalent in CKD and leads to increased vascular stiffness and cardiovascular disease (CVD). Non-traditional cardiovascular risk factors include abnormal bone turnover and/or dysregulation of the...
10.
Ultrasound reduces the minimum effective local anaesthetic volume compared with peripheral nerve stimulation for interscalene block
McNaught A, Shastri U, Carmichael N, Awad I, Columb M, Cheung J, et al.
Br J Anaesth . 2010 Nov; 106(1):124-30. PMID: 21059701
Background: Previous studies have demonstrated that lower local anaesthetic (LA) volumes can be used for ultrasound (US)-guided interscalene brachial plexus block (ISB). However, no study has examined whether US can...