J C Paton
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Explore the profile of J C Paton including associated specialties, affiliations and a list of published articles.
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114
Citations
5292
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Recent Articles
1.
Briles D, Paton J, Mukerji R, Swiatlo E, Crain M
Microbiol Spectr
. 2019 Dec;
7(6).
PMID: 31858954
is a Gram-Positive pathogen that is a major causative agent of pneumonia, otitis media, sepsis and meningitis across the world. The World Health Organization estimates that globally over 500,000 children...
2.
Shewell L, Wang J, Paton J, Paton A, Day C, Jennings M
Biochem Biophys Res Commun
. 2018 Nov;
507(1-4):173-177.
PMID: 30415777
N-glycolylneuraminic acid (Neu5Gc)-containing glycans are a prominent form of aberrant glycosylation found in human tumor cells and have been proposed as cancer biomarkers. The B subunit of the subtilase cytotoxin...
3.
Oliver E, Pope C, Clarke E, Langton Hewer C, Ogunniyi A, Paton J, et al.
Clin Exp Immunol
. 2018 Oct;
195(2):213-225.
PMID: 30325010
Pneumococcal infections cause a large global health burden, and the search for serotype-independent vaccines continues. Existing conjugate vaccines reduce nasopharyngeal colonization by target serotypes. Such mucosal effects of novel antigens...
4.
van Lidth de Jeude J, Meijer B, Wielenga M, Spaan C, Baan B, Rosekrans S, et al.
Oncogene
. 2016 Nov;
36(24):3397-3405.
PMID: 27819675
Intestinal epithelial stem cells are highly sensitive to differentiation induced by endoplasmic reticulum (ER) stress. Colorectal cancer develops from mutated intestinal epithelial stem cells. The most frequent initiating mutation occurs...
5.
Mubarak A, Ahmed M, Upile N, Vaughan C, Xie C, Sharma R, et al.
Clin Microbiol Infect
. 2016 Jun;
22(8):736.e1-7.
PMID: 27256063
Pneumococcal carriage is common in young children, which may account for the high incidence of disease in this age group. Host factors determining the clearance of carriage in humans remain...
6.
Paton J, Paton A
Kidney Int
. 2006 Dec;
70(12):2049-51.
PMID: 17136129
The pathway and the efficiency of intracellular trafficking of Shiga toxin differ between cell types, and this impacts on susceptibility to cytotoxicity. Warnier et al. demonstrate that in cell types...
7.
Paton J, Giammarinaro P
Trends Microbiol
. 2002 Feb;
9(11):515-8.
PMID: 11825689
No abstract available.
8.
Paton A, Srimanote P, Woodrow M, Paton J
Infect Immun
. 2001 Oct;
69(11):6999-7009.
PMID: 11598075
The capacity of Shiga toxigenic Escherichia coli (STEC) to adhere to the intestinal mucosa undoubtedly contributes to pathogenesis of human disease. The majority of STEC strains isolated from severe cases...
9.
Brown J, Ogunniyi A, Woodrow M, Holden D, Paton J
Infect Immun
. 2001 Oct;
69(11):6702-6.
PMID: 11598041
There has been considerable recent research into protein based Streptococcus pneumoniae vaccines as alternatives to the existing capsular antigen vaccines. PiuA and PiaA (formerly Pit1A and Pit2A) are recently identified...
10.
Ogunniyi A, Woodrow M, Poolman J, Paton J
Infect Immun
. 2001 Sep;
69(10):5997-6003.
PMID: 11553536
The need for the development of cheap and effective vaccines against pneumococcal disease has necessitated the evaluation of common virulence-associated proteins of Streptococcus pneumoniae as potential vaccine antigens. In this...