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J C Bornstein

Explore the profile of J C Bornstein including associated specialties, affiliations and a list of published articles. Areas
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Articles 126
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Recent Articles
11.
Tan L, Bornstein J, Anderson C
Neurogastroenterol Motil . 2009 May; 21(9):994-1001. PMID: 19413682
Whilst much is known about the function and influence of vagal afferents on the mammalian upper gastrointestinal tract, the phenotypes of the different types of vagal afferent neurons innervating the...
12.
Tan L, Bornstein J, Anderson C
Neuroscience . 2008 Aug; 156(2):334-43. PMID: 18706490
Physiological studies suggest visceral spinal afferents are generally small diameter, unmyelinated C-fibers or myelinated Adelta-fibers, but little is known about the size and chemical phenotypes of visceral sensory neurons supplying...
13.
Monro R, Bornstein J, Bertrand P
Neurogastroenterol Motil . 2008 Jul; 20(10):1165-73. PMID: 18643893
Stimulation of the myenteric plexus results in activation of submucosal neurons and dilation of arterioles, one way that motility and secretion can be coupled together. The present study aimed to...
14.
Gwynne R, Bornstein J
Curr Neuropharmacol . 2008 Jul; 5(1):1-17. PMID: 18615154
Digestion and absorption of nutrients and the secretion and reabsorption of fluid in the gastrointestinal tract are regulated by neurons of the enteric nervous system (ENS), the extensive peripheral nerve...
15.
Bornstein J
Purinergic Signal . 2008 Mar; 4(3):197-212. PMID: 18368521
For many years, ATP and adenosine have been implicated in movement regulation of the gastrointestinal tract. They act through three major receptor subtypes: adenosine or P1 receptors, P2X receptors and...
16.
Neal K, Bornstein J
Neurogastroenterol Motil . 2007 Dec; 20(5):566-75. PMID: 18086206
Polarized outputs of myenteric interneurons in guinea-pig small intestine have been well studied. However, the variety of motility patterns exhibited suggests that some interneuron targets remain unknown. We used antisera...
17.
Larsson M, Simren M, Thomas E, Bornstein J, Lindstrom E, Sjovall H
Neurogastroenterol Motil . 2007 Sep; 19(10):812-20. PMID: 17883433
The pathophysiology of irritable bowel syndrome (IBS) is complex and incompletely known. Very little has been studied regarding the role of submucous neuronal activity. We therefore measured small intestinal transmural...
18.
Gwynne R, Bornstein J
Am J Physiol Gastrointest Liver Physiol . 2007 Mar; 292(6):G1660-70. PMID: 17347449
The motility of the gut depends on the chemicals contained in the lumen, but the stimuli that modify motility and their relationship to enteric neural pathways are unclear. This study...
19.
Neal K, Bornstein J
Neuroscience . 2007 Jan; 145(2):556-67. PMID: 17261354
5-HT released by gastrointestinal mucosa and enteric interneurons has powerful effects on gut behavior. However, the targets of 5-HT-containing neurons within enteric circuits are not well characterized. We used antisera...
20.
Gwynne R, Bornstein J
Am J Physiol Gastrointest Liver Physiol . 2007 Jan; 292(4):G1162-72. PMID: 17218474
Mechanisms underlying nutrient-induced segmentation within the gut are not well understood. We have shown that decanoic acid and some amino acids induce neurally dependent segmentation in guinea pig small intestine...