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J C Bizot

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Articles 18
Citations 188
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Recent Articles
1.
Picard M, Morisset S, Cloix J, Bizot J, Guerin M, Beneteau V, et al.
Neuroscience . 2010 Jun; 169(3):1337-46. PMID: 20580787
A novel pyridine derivative, 8-{4-[(6-methoxy-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-3-ylmethyl)-amino]-butyl}-8-aza-spiro[4.5]decane-7,9-dione hydrochloride, termed JB-788, was designed to selectively target 5-HT(1A) receptors. In the present study, the pharmacological profile of JB-788 was characterized in vitro using radioligands...
2.
Bonnet N, Bernard P, Beaupied H, Bizot J, Trovero F, Courteix D, et al.
Toxicol Appl Pharmacol . 2007 Mar; 221(1):111-8. PMID: 17383703
The aim of this study was to evaluate the effects of various drugs which present antidepressant properties: selective serotonin-reuptake inhibitors (SSRIs, fluoxetine), serotonin and noradrenaline-reuptake inhibitors (Desipramine) and phosphodiesterase inhibitors...
3.
Houpert P, Bizot J, Bussy C, Dhieux B, Lestaevel P, Gourmelon P, et al.
Int J Radiat Biol . 2007 Mar; 83(2):99-104. PMID: 17357431
Purpose: A radionuclide that accumulates in the central nervous system is likely to exert both a chemical and a radiological effect. The present study aimed at assessing the behavioral effect...
4.
Baille V, Dorandeu F, Carpentier P, Bizot J, Filliat P, Four E, et al.
Pharmacol Biochem Behav . 2001 Aug; 69(3-4):561-9. PMID: 11509217
Effects of low to mild doses of soman on central and blood cholinesterase (ChE) activities and anxiety behavior were studied in mice 30 min, 24 h and 7 days after...
5.
Puma C, Bizot J
Neuroreport . 1999 Aug; 10(11):2297-300. PMID: 10439452
The present study describes the effects of intraseptal infusions of 1 nmol AMPA and 12 nmol NBQX on both frequency and amplitude of physostigmine-induced theta rhythm in urethane-anesthetized rats. Infusion...
6.
Puma C, Deschaux O, Molimard R, Bizot J
Eur Neuropsychopharmacol . 1999 Jul; 9(4):323-7. PMID: 10422893
Nicotine was investigated for its mnemonic effect in a two trials object recognition task. In the first trial, two copies of the same object were presented. In the second trial...
7.
Puma C, Bizot J
Neurosci Lett . 1998 Jul; 248(3):183-6. PMID: 9654339
The present study describes the effects of intraseptal microinjections of 2 nmol of AP5 upon memory of rats subjected to a two trial object recognition task. This task allows us...
8.
Trovero F, Brochet D, Breton P, Tambute A, Begos A, Bizot J
Toxicol Appl Pharmacol . 1998 Jul; 150(2):321-7. PMID: 9653063
This study consists of two parts, first to compare the pharmacological profile of atropine and CEB-1957 substance toward muscarinic receptor subtypes. In various rat brain structures, binding properties were determined...
9.
Breton P, Bizot J, Buee J, De La Manche I
Toxicon . 1998 Jun; 36(4):645-55. PMID: 9643478
The neurotoxicity of Penitrem A (PA) in rats was assessed against neurophysiological, behavioral and histopathological parameters. Animals were acutely given intracerebroventricular (22-45 mg) or intraperitoneal injections (0.5-1.5 mg/kg) of PA....
10.
Bizot J
Pharmacol Biochem Behav . 1998 May; 59(4):1069-80. PMID: 9586869
The effects of various drugs were assessed in rats responding under a Differential-Reinforcement-of-Low-Rate 30-s (DRL 30-s) schedule. Atropine, scopolamine, and CEB-1957 (a new muscarinic blocker) increased response rate and decreased...