J Bruce McCallum
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Explore the profile of J Bruce McCallum including associated specialties, affiliations and a list of published articles.
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12
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433
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Recent Articles
1.
McCallum J, Pillay S, Vizuete J, Mouradian G, Hudetz A, Stekiel T
Anesthesiology
. 2013 Jan;
118(2):350-60.
PMID: 23287707
Introduction: Previously observed increased sensitivity to noxious stimulation in the Dahl salt-sensitive rat strain (SS/JrHsdMcwi, abbreviated as SS) compared to Brown Norway rats (BN/NhsdMcwi abbreviated as BN) is mediated by...
2.
Tang Q, Bangaru M, Kostic S, Pan B, Wu H, Koopmeiners A, et al.
J Neurosci
. 2012 Aug;
32(34):11737-49.
PMID: 22915116
Currents through voltage-gated Ca²⁺ channels (I(Ca)) may be regulated by cytoplasmic Ca²⁺ levels ([Ca²⁺](c)), producing Ca²⁺-dependent inactivation (CDI) or facilitation (CDF). Since I(Ca) regulates sensory neuron excitability, altered CDI or...
3.
Bangaru M, Park F, Hudmon A, McCallum J, Hogan Q
J Mol Neurosci
. 2011 Aug;
46(3):497-504.
PMID: 21863315
Stably expressed housekeeping genes (HKGs) are necessary for standardization of transcript measurement by quantitative real-time polymerase chain reaction (qRT-PCR). Peripheral nerve injury disrupts expression of numerous genes in sensory neurons,...
4.
Pillay S, Vizuete J, McCallum J, Hudetz A
Anesthesiology
. 2011 Aug;
115(4):733-42.
PMID: 21804378
Background: The nucleus basalis of Meynert of the basal forebrain has been implicated in the regulation of the state of consciousness across normal sleep-wake cycles. Its role in the modulation...
5.
Kawano T, Zoga V, Gemes G, McCallum J, Wu H, Pravdic D, et al.
Proc Natl Acad Sci U S A
. 2009 May;
106(21):8725-30.
PMID: 19439665
Painful axotomy decreases K(ATP) channel current (IK(ATP)) in primary afferent neurons. Because cytosolic Ca(2+) signaling is depressed in injured dorsal root ganglia (DRG) neurons, we investigated whether Ca(2+)-calmodulin (CaM)-Ca(2+)/CaM-dependent kinase...
6.
Kawano T, Zoga V, Kimura M, Liang M, Wu H, Gemes G, et al.
Mol Pain
. 2009 Mar;
5:12.
PMID: 19284878
Background: ATP-sensitive potassium (KATP) channels in neurons regulate excitability, neurotransmitter release and mediate protection from cell-death. Furthermore, activation of KATP channels is suppressed in DRG neurons after painful-like nerve injury....
7.
Sarantopoulos C, McCallum J, Rigaud M, Fuchs A, Kwok W, Hogan Q
Brain Res
. 2006 Dec;
1132(1):84-99.
PMID: 17184741
Unlabelled: Calcium-activated potassium channels regulate AHP and excitability in neurons. Since we have previously shown that axotomy decreases I(Ca) in DRG neurons, we investigated the association between I(Ca) and K((Ca))...
8.
McCallum J, Kwok W, Sapunar D, Fuchs A, Hogan Q
Anesthesiology
. 2006 Jul;
105(1):160-8.
PMID: 16810008
Background: Reports of Ca(2+) current I(Ca) loss after injury to peripheral sensory neurons do not discriminate between axotomized and spared neurons. The spinal nerve ligation model separates axotomized from spared...
9.
Sapunar D, Ljubkovic M, Lirk P, McCallum J, Hogan Q
Anesthesiology
. 2005 Jul;
103(2):360-76.
PMID: 16052119
Background: Painful peripheral nerve injury results in disordered sensory neuron function that contributes to the pathogenesis of neuropathic pain. However, the relative roles of neurons with transected axons versus intact...
10.
Sarantopoulos C, McCallum J, Kwok W, Hogan Q
J Neurosci Methods
. 2004 Sep;
139(1):61-8.
PMID: 15351522
Perforated patch recordings of neuronal calcium currents (I(Ca)) with amphotericin B or nystatin reduce dialysis of intracellular constituents and current rundown, but can be difficult and frequently unsuccessful. We investigated...