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J Brennum

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Articles 38
Citations 472
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Recent Articles
11.
Mikkelsen S, Jorgensen H, Larsen P, Brennum J, Dahl J
Reg Anesth Pain Med . 2000 Sep; 25(5):452-8. PMID: 11009229
Background And Objectives: Ketamine is an N-methyl-D-aspartate (NMDA) receptor antagonist, and has been proven effective in alleviating secondary hyperalgesia in human subjects when injected intravenously. After oral ingestion, ketamine is...
12.
Danielsen E, Brennum J, Thomsen C
Ugeskr Laeger . 2000 Mar; 162(7):941. PMID: 10740438
No abstract available.
13.
Mikkelsen S, Ilkjaer S, Brennum J, Borgbjerg F, Dahl J
Anesthesiology . 1999 Jun; 90(6):1539-45. PMID: 10360849
Background: The (NMDA) receptor plays a significant role in wind-up and spinal hypersensitivity and is involved in the occurrence of secondary hyperalgesia. Ketamine is an NMDA-receptor antagonist and has proven...
14.
Ilkjaer S, Nikolajsen L, Hansen T, Wernberg M, Brennum J, Dahl J
Br J Anaesth . 1999 Apr; 81(5):707-12. PMID: 10193280
We studied 60 patients undergoing operation on the kidney with combined general and epidural anaesthesia, in a double-blind, randomized, controlled study. Patients were allocated to receive a preoperative bolus dose...
15.
Ilkjaer S, Dirks J, Brennum J, Wernberg M, Dahl J
Br J Anaesth . 1998 Jan; 79(5):600-5. PMID: 9422898
Dextromethorphan is a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist known to inhibit wind-up and central hyperexcitability of dorsal horn neurones. We studied 24 healthy, unmedicated male volunteers, aged 21-28 yr, in...
16.
Thomsen L, Brennum J, Iversen H, Olesen J
Ugeskr Laeger . 1997 Jul; 159(30):4645-8. PMID: 9245041
The purpose of the present study was to examine the effect of the nitric oxide (NO) donor glyceryl trinitrate (GTN) on nociceptive thresholds in man. On two different study days...
17.
Petersen K, Brennum J, Dahl J
Pain . 1997 Apr; 70(2-3):167-74. PMID: 9150290
The analgesic effect of systemic ibuprofen was investigated with two human experimental pain models: (i) static mechanical stimulation of the inter digital web between the 2nd and 3rd finger and...
18.
Bendtsen L, Jensen R, Brennum J, Arendt-Nielsen L, Olesen J
Cephalalgia . 1996 Jun; 16(4):251-6. PMID: 8792037
The aim of the present study was to compare the late exteroceptive suppression period (ES2) of temporalis muscle activity between patients with chronic tension-type headache and healthy controls, and to...
19.
Ilkjaer S, Petersen K, Brennum J, Wernberg M, Dahl J
Br J Anaesth . 1996 Jun; 76(6):829-34. PMID: 8679358
Ketamine reduces nociception by binding noncompetitively to the N-methyl-D-aspartate (NMDA) receptor, activation of which increases spinal hypersensitivity. We studied 19 healthy, unmedicated male volunteers, aged 20-31 yr. Burn injuries were...
20.
Thomsen L, Brennum J, Iversen H, Olesen J
Cephalalgia . 1996 May; 16(3):169-74. PMID: 8734768
Several animal studies suggest that nitric oxide (NO) plays a role in central and peripheral modulation of nociception. Glyceryl trinitrate (GTN) exerts its physiological actions via donation of NO. The...