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J B Rimmler

Explore the profile of J B Rimmler including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 1026
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Recent Articles
1.
Ashley-Koch A, Shao Y, Rimmler J, Gaskell P, Welsh-Bohmer K, Jackson C, et al.
Neurosci Lett . 2005 Apr; 379(3):199-204. PMID: 15843063
Apolipoprotein E (APOE) is the only universally confirmed susceptibility gene for late-onset Alzheimer disease (LOAD), although many loci are believed to modulate LOAD risk. The genetic homogeneity of isolated populations,...
2.
Kenealy S, Babron M, Bradford Y, Schnetz-Boutaud N, Haines J, Rimmler J, et al.
Am J Hum Genet . 2004 Oct; 75(6):1070-8. PMID: 15494893
Multiple sclerosis (MS) is a debilitating neuroimmunological and neurodegenerative disorder. Despite substantial evidence for polygenic inheritance of the disease, the major histocompatibility complex is the only region that clearly and...
3.
Barcellos L, Oksenberg J, Green A, Bucher P, Rimmler J, Schmidt S, et al.
Brain . 2002 Feb; 125(Pt 1):150-8. PMID: 11834600
Multiple sclerosis is a clinically heterogeneous demyelinating disease and an important cause of acquired neurological disability. An underlying complex genetic susceptibility plays an important role in multiple sclerosis aetiology; however,...
4.
Pericak-Vance M, Rimmler J, Martin E, Haines J, Garcia M, Oksenberg J, et al.
Neurogenetics . 2001 Nov; 3(4):195-201. PMID: 11714099
Multiple sclerosis (MS) is an autoimmune neurological disorder with a complex etiology. Sibling risk, twin, and adoption studies have demonstrated that genes play a vital role in susceptibility to MS....
5.
Green A, Barcellos L, Rimmler J, Garcia M, Caillier S, Lincoln R, et al.
J Neuroimmunol . 2001 Apr; 116(1):116-24. PMID: 11311337
Genome screenings in multiple sclerosis (MS) have identified multiple susceptibility regions supporting a polygenic model for this disease. Evidence for linkage was consistently observed at ch.19q13 suggesting the presence of...
6.
Barcellos L, Schito A, Rimmler J, Vittinghoff E, Shih A, Lincoln R, et al.
Immunogenetics . 2000 May; 51(4-5):281-8. PMID: 10803840
Multiple sclerosis (MS) is a common disease of the central nervous system characterized by myelin loss and progressive neurological dysfunction. An underlying genetic susceptibility plays a clear role in the...
7.
Siddique T, Pericak-Vance M, Caliendo J, Hong S, Hung W, Kaplan J, et al.
Neurogenetics . 2000 Mar; 1(3):213-6. PMID: 10737125
Amyotrophic lateral sclerosis (ALS) is a neuro-degenerative disorder with both sporadic and familial forms. Approximately 20% of autosomal dominant ALS is caused by mutations in the Cu/Zn superoxide dismutase (SOD1)...
8.
Seboun E, Oksenberg J, Rombos A, Usuku K, Goodkin D, Lincoln R, et al.
Neurogenetics . 1999 Dec; 2(3):155-62. PMID: 10541588
Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system. A complex genetic etiology is thought to underlie susceptibility to this disease. The present study was designed...
9.
Haines J, Terwedow H, Burgess K, Pericak-Vance M, Rimmler J, Martin E, et al.
Hum Mol Genet . 1998 Jul; 7(8):1229-34. PMID: 9668163
Multiple sclerosis (MS) is a demyelinating autoimmune disease of the central nervous system. While its etiology is not well understood, genetic factors are clearly involved. Until recently, most genetic studies...
10.
Xia Y, Rohan De Silva H, Rosi B, Yamaoka L, Rimmler J, Pericak-Vance M, et al.
Ann Neurol . 1996 Aug; 40(2):207-15. PMID: 8773602
The non-Abeta component of Alzheimer's disease amyloid (NAC) is copurified with amyloid from the brain tissue of Alzheimer's disease victims and is immunohistochemically localized to amyloid fibrils. NAC is a...