J B Orens
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Explore the profile of J B Orens including associated specialties, affiliations and a list of published articles.
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33
Citations
401
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Recent Articles
1.
Magruder J, Shah A, Crawford T, Grimm J, Kim B, Orens J, et al.
Am J Transplant
. 2016 Sep;
17(2):485-495.
PMID: 27618731
We simulated the impact of regionalization of isolated heart and lung transplantation within United Network for Organ Sharing (UNOS) regions. Overall, 12 594 orthotopic heart transplantation (OHT) patients across 135...
2.
Orandi B, Lonze B, Jackson A, Terezakis S, Kraus E, Alachkar N, et al.
Am J Transplant
. 2016 May;
16(10):3041-3045.
PMID: 27214874
Patients requiring desensitization prior to renal transplantation are at risk for developing severe antibody-mediated rejection (AMR) refractory to treatment with plasmapheresis and intravenous immunoglobulin (PP/IVIg). We have previously reported success...
3.
Akulian J, Pipeling M, John E, Orens J, Lechtzin N, McDyer J
Am J Transplant
. 2012 Sep;
13(1):146-56.
PMID: 23016698
The maintenance of CMV-specific T cell memory in lung transplant recipients (LTRs) is critical for host defense and allograft durability, particularly in donor(+) /recipient(-) (D(+) R(-) ) individuals who demonstrate...
4.
Shah P, West E, Whitlock A, Orens J, McDyer J
Am J Transplant
. 2009 Dec;
9(12):2697-706.
PMID: 20021479
Obliterative bronchiolitis (OB) limits the long-term success of lung transplantation, while T-cell effector mechanisms in this process remain incompletely understood. Using the murine heterotopic tracheal transplant model of obliterative airway...
5.
Orens J
Int J Clin Pract Suppl
. 2008 Feb;
(158):4-9.
PMID: 18078388
Lung transplantation is an accepted therapeutic intervention for patients with pulmonary arterial hypertension (PAH) who fail medical therapy. Highly selected candidates with PAH may enjoy improved survival by combining medical...
6.
Orens J, Shearon T, Freudenberger R, Freudenburger R, Conte J, Bhorade S, et al.
Am J Transplant
. 2006 Apr;
6(5 Pt 2):1188-97.
PMID: 16613595
This article reviews trends in thoracic organ transplantation based on OPTN/SRTR data from 1995 to 2004. The number of active waiting list patients for heart transplants continues to decline, primarily...
7.
Gaine S, Orens J
Semin Respir Crit Care Med
. 2005 Aug;
22(5):533-40.
PMID: 16088699
Although lung transplantation is a viable option for patients with end-stage pulmonary hypertension, it is associated with numerous problems including infection, rejection, and limited long-term survival. Because of these limitations,...
8.
Studer S, Levy R, McNeil K, Orens J
Eur Respir J
. 2004 Oct;
24(4):674-85.
PMID: 15459149
The success of lung transplantation has improved over time as evidenced by better long-term survival and functional outcomes. Despite the success of this procedure, there are numerous problems and complications...
9.
Brock M, Borja M, Ferber L, Orens J, Anzcek R, Krishnan J, et al.
J Heart Lung Transplant
. 2001 Dec;
20(12):1282-90.
PMID: 11744411
Background: Because acute rejection is associated with inferior outcomes in lung transplantation, we have routinely employed OKT3, anti-thymocyte globulin (ATG), or daclizumab as adjuncts to reduce rejection. Method: We performed...
10.
Conte J, Borja M, Patel C, Yang S, Jhaveri R, Orens J
Ann Thorac Surg
. 2001 Nov;
72(5):1673-9; discussion 1679-80.
PMID: 11722064
Background: Single lung transplantation (SLT) and bilateral lung transplantation (BLT) are routinely performed in patients with primary pulmonary hypertension (PPH) and secondary pulmonary hypertension (SPH). It is unclear which procedure...