J Alex Grizzell
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Explore the profile of J Alex Grizzell including associated specialties, affiliations and a list of published articles.
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20
Citations
284
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Recent Articles
1.
Grizzell J, Clarity T, Rodriguez R, Marshall Z, Cooper M
Brain Behav Immun
. 2024 Aug;
122:353-367.
PMID: 39187049
Chronic stress increases activity of the brain's innate immune system and impairs function of the medial prefrontal cortex (mPFC). However, whether acute stress triggers similar neuroimmune mechanisms is poorly understood....
2.
Grizzell J, Vanbaelinghem M, Westerman J, Saddoris M
Stress
. 2023 Nov;
26(1):2278315.
PMID: 37916300
Alcohol use during adolescence coincides with elevated risks of stress-related impairment in adults, particularly via disrupted developmental trajectories of vulnerable corticolimbic and mesolimbic systems involved in fear processing. Prior work...
3.
Grizzell J, Vanbaelinghem M, Westerman J, Saddoris M
bioRxiv
. 2023 Oct;
PMID: 37873067
Alcohol use during adolescence coincides with elevated risks of stress-related impairment in adults, particularly via disrupted developmental trajectories of vulnerable corticolimbic and mesolimbic systems involved in fear processing. Prior work...
4.
Cooper M, Grizzell J, Whitten C, Burghardt G
Neurosci Biobehav Rev
. 2023 Feb;
147:105102.
PMID: 36804399
Syrian hamsters show complex social play behavior and provide a valuable animal model for delineating the neurobiological mechanisms and functions of social play. In this review, we compare social play...
5.
Cooper M, Clinard C, Dulka B, Grizzell J, Loewen A, Campbell A, et al.
Psychoneuroendocrinology
. 2021 May;
129:105249.
PMID: 33971475
Social experience can generate neural plasticity that changes how individuals respond to stress. Winning aggressive encounters alters how animals respond to future challenges and leads to increased plasma testosterone concentrations...
6.
Grizzell J, Clarity T, Graham N, Dulka B, Cooper M
Front Neural Circuits
. 2020 Nov;
14:50.
PMID: 33177993
The ventromedial prefrontal cortex (vmPFC) plays a critical role in stress resilience through top-down inhibition of key stress-sensitive limbic and hindbrain structures, including the dorsal raphe nucleus (DRN). In a...
7.
Dulka B, Bagatelas E, Bress K, Grizzell J, Cannon M, Whitten C, et al.
Sci Rep
. 2020 Apr;
10(1):6884.
PMID: 32327679
Tremendous individual differences exist in stress responsivity and social defeat stress is a key approach for identifying cellular mechanisms of stress susceptibility and resilience. Syrian hamsters show reliable territorial aggression,...
8.
Iarkov A, Barreto G, Grizzell J, Echeverria V
Front Aging Neurosci
. 2020 Feb;
12:4.
PMID: 32076403
Parkinson's disease (PD) is the second-leading cause of dementia and is characterized by a progressive loss of dopaminergic neurons in the substantia nigra alongside the presence of intraneuronal α-synuclein-positive inclusions....
9.
Dulka B, Bress K, Grizzell J, Cooper M
Neuroscience
. 2018 Aug;
388:274-283.
PMID: 30075245
Stress is a contributing factor in the etiology of several mood and anxiety disorders, and social defeat models are used to investigate the biological basis of stress-related psychopathologies. Male Syrian...
10.
Dulka B, Koul-Tiwari R, Grizzell J, Harvey M, Datta S, Cooper M
Stress
. 2018 Jun;
:1-6.
PMID: 29932809
Stress is a well-known risk factor for psychopathology and rodent models of social defeat have strong face, etiological, construct and predictive validity for these conditions. Syrian hamsters are highly aggressive...