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J Accaputo

Explore the profile of J Accaputo including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 2
Citations 24
Followers 0
Related Specialty
Pharmacology
Co-Authors
K S Pang
W F Cherry
A J Schwab
C A GORESKY
S Fayz
V Yuen
W F Lee
Published In
J Pharmacokinet Biopharm
J Pharmacol Exp Ther
Affiliations
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Recent Articles
1.
Effects of perfusate flow rate on measured blood volume, disse space, intracellular water space, and drug extraction in the perfused rat liver preparation: characterization by the multiple indicator dilution technique
Pang K, Lee W, Cherry W, Yuen V, Accaputo J, Fayz S, et al.
J Pharmacokinet Biopharm . 1988 Dec; 16(6):595-632. PMID: 3074996
The effect of hepatic blood flow on the elimination of several highly cleared substrates was studied in the once-through perfused rat liver preparation. A constant and low input concentration of...
2.
Combined hepatic arterial-portal venous and hepatic arterial-hepatic venous perfusions to probe the abundance of drug metabolizing activities: perihepatic venous O-deethylation activity for phenacetin and periportal sulfation activity for...
Pang K, Cherry W, Accaputo J, Schwab A, GORESKY C
J Pharmacol Exp Ther . 1988 Nov; 247(2):690-700. PMID: 3183964
Although normal-retrograde liver perfusion allows definition of relative distribution patterns of multienzyme systems involved in parallel, competing and sequential metabolic pathways, the technique fails to describe localization patterns for unienzyme...