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J A van Hilten

Explore the profile of J A van Hilten including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 16
Citations 64
Followers 0
Related Specialties
Hematology
General Medicine
General Surgery
Top 10 Co-Authors
A Brand
I L Bonta
S Ben Efraim
L M G van de Watering
J J Zwaginga
G R Elliott
R J M Klautz
C Prowse
R Y Dodd
O Akerblom
Published In
Prostaglandins Leukot Essent Fatty Acids
Vox Sang
Br J Surg
Transfus Med
Eur J Biochem
Affiliations
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Recent Articles
11.
The use of the divalent calcium-ionophore A23187 as a biochemical tool in pharmacological and in vitro toxicological studies
Boot J, van Hilten J
Cell Struct Funct . 1996 Apr; 21(2):97-9. PMID: 8790938
The use of A23187 as a biochemical tool is described. A23187 was used to elucidate the mechanisms of intracellular transport and secretion of N-hydroxylated aniline metabolites in rat hepatocyte primary...
12.
Characterization of macrophage proteins bearing the functional leukotriene D4-binding site of an anti-cysteinylleukotriene monoclonal antibody
van Hilten J, Brune K, Bickel D, Mollenhauer J
Eur J Biochem . 1993 May; 214(1):83-90. PMID: 7685282
Protein conformations of the putative cysteinylleukotriene (LT) receptor of macrophages were characterized using anti-idiotypic IgG (AIAb) against an anti-LT monoclonal Ab (LTmAb). The AIAb nature of two rabbit antisera were...
13.
Leukotriene C4 is an essential 5-lipoxygenase intermediate in A23187-induced macrophage cytostatic activity against P815 tumor cells
van Hilten J, Ben Efraim S, Zijlstra F, Bonta I
Prostaglandins Leukot Essent Fatty Acids . 1990 Apr; 39(4):283-90. PMID: 2112758
Resident peritoneal macrophages incubated with 3.5 x 10(-7) M Calcium ionophore A23187 in tumor cell growth medium (TGM) release large amounts of leukotriene (LT)E4 and an unidentified 5-lipoxygenase product, whereas...
14.
Calcium-ionophore A23187 induces dual changes in the release of 5-lipoxygenase and cyclooxygenase products by macrophages
van Hilten J, Ben Efraim S, Bonta I
Arch Int Pharmacodyn Ther . 1990 Mar; 304:55-63. PMID: 2173505
A23187-treated murine peritoneal macrophages release increased quantities of the immunoreactive 5-lipoxygenase metabolite leukotriene B4 (LTB4) and the immunoreactive cyclooxygenase products 6-keto prostaglandin F1 alpha (6-keto PGF1 alpha) and thromboxane B2...
15.
Endogenous lipoxygenase metabolites mediate A23187 induced macrophage cytostasis towards P815 tumor cells in vitro
van Hilten J, Elliott G, Bonta I
Agents Actions . 1989 Jan; 26(1-2):170-2. PMID: 2496588
The calcium ionophore A23187 stimulated cytostatic activity of peritoneal macrophages towards P815 tumor cells in coculture served as a model for macrophage activation. A macrophage enriched preparation, separated on the...
16.
Specific lipoxygenase inhibition reverses macrophage cytotasis towards P815 tumor cells in vitro induced by the calcium ionophore A23187
van Hilten J, Elliott G, Bonta I
Prostaglandins Leukot Essent Fatty Acids . 1988 Dec; 34(3):187-92. PMID: 3146755
A23187-stimulated cytostatic activity of peritoneal macrophages towards P815 tumor cells served as a model for macrophage activation: a macrophage enriched preparation, separated on the basis of cell size in a...