J A Summerfield
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Explore the profile of J A Summerfield including associated specialties, affiliations and a list of published articles.
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88
Citations
1312
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Recent Articles
1.
Summerfield J
Biochem Soc Trans
. 2003 Jul;
31(Pt 4):770-3.
PMID: 12887301
Mannose-binding lectin (MBL; also known as mannan-binding lectin) is an important component of innate immunity. MBL levels are mainly genetically determined. Low serum MBL levels and their cognate haplotypes have...
2.
Baxter N, Sumiya M, Cheng S, Erlich H, Regan L, Simons A, et al.
Clin Exp Immunol
. 2001 Dec;
126(3):529-34.
PMID: 11737072
Variant alleles of the mannose binding lectin (MBL) gene are associated with increased susceptibility to infection and polymorphisms of tumour necrosis factor and lymphotoxin alpha genes (TNF, LTA) are associated...
3.
Summerfield J
J R Coll Physicians Lond
. 2000 Sep;
34(4):381-5.
PMID: 11005078
Currently seven viruses, A, B, C, D, E, G and transfusion transmitted virus (TTV), are recognised in the hepatitis virus alphabet. Hepatitis G virus and TTV probably do not cause...
4.
Hibberd M, Sumiya M, Summerfield J, Booy R, Levin M
Lancet
. 1999 Apr;
353(9158):1049-53.
PMID: 10199352
Background: The reasons why meningococcal disease develops in only a small proportion of individuals carrying the causative bacteria are unknown. Differences in host responses to bacterial colonisation are thought to...
5.
McBride M, Fischer P, Sumiya M, McClure M, Turner M, Skinner C, et al.
Int J STD AIDS
. 1998 Dec;
9(11):683-8.
PMID: 9863582
This study set out to investigate whether plasma mannose-binding protein (MBP) deficiency caused by mutations in the MBP gene associates with pyogenic or opportunistic infections in HIV-infected patients. Plasma samples...
6.
Thomas S, BOOTH J, Levine T, Regan L, Summerfield J
Lancet
. 1998 Aug;
352(9125):366.
PMID: 9717925
No abstract available.
7.
Teare J, Daly C, Rodgers C, Padley S, Coker R, Main J, et al.
Genitourin Med
. 1997 Aug;
73(4):271-3.
PMID: 9389948
Objectives: Biliary tract abnormalities are well recognised in AIDS, most frequently related to opportunistic infection with Cryptosporidium, Microsporidium, and cytomegalovirus. We noted a high frequency of pancreatic abnormalities associated with...
8.
Summerfield J, Sumiya M, Levin M, Turner M
BMJ
. 1997 Apr;
314(7089):1229-32.
PMID: 9154025
Objective: To determine the extent to which mutations in the mannose binding protein gene predispose to childhood infection. Design: Clinical details and genotype of mannose binding protein determined in consecutive...
9.
Sumiya M, Summerfield J
Semin Liver Dis
. 1997 Jan;
17(4):311-8.
PMID: 9408966
Mannose-binding protein (MBP) belongs to a group of Ca(2+)-dependent lectins called collectins that play a role in first-line host defense. It recognizes specific carbohydrate residues (mannose and N-acetylglucosamine) on the...
10.
Thomas H, Foster G, Sumiya M, McIntosh D, Jack D, Turner M, et al.
Lancet
. 1996 Nov;
348(9039):1417-9.
PMID: 8965590
Background: Persistent with hepatitis B virus (HBV) affects 350 million people worldwide, and 20-40% of infected patients die of cirrhosis and liver cancer. Little is known about the host factors...