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J A Ruggles

Explore the profile of J A Ruggles including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 149
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Recent Articles
1.
Amiel S, Heller S, MacDonald I, Schwartz S, Klaff L, Ruggles J, et al.
Diabetes Obes Metab . 2005 Jul; 7(5):504-16. PMID: 16050943
Background: Pramlintide, a human amylin analogue, is a potential new adjunctive therapy to insulin for patients with type 1 diabetes and insulin-using patients with type 2 diabetes. Early clinical trials...
2.
Classen S, Ruggles J, SCHULTZ S
J Mol Biol . 2001 Dec; 314(5):1113-25. PMID: 11743727
Oxytricha nova telomere end-binding protein specifically recognizes and caps single strand (T(4)G(4))(n) telomeric DNA at the very 3'-ends of O. nova macronuclear chromosomes. Proteins homologous to the N-terminal domain of...
3.
Horvath M, Schweiker V, Bevilacqua J, Ruggles J, SCHULTZ S
Cell . 1999 Jan; 95(7):963-74. PMID: 9875850
Telomeres are specialized protein-DNA complexes that compose the ends of eukaryotic chromosomes. Telomeres protect chromosome termini from degradation and recombination and act together with telomerase to ensure complete genome replication....
4.
Ruggles J, Nemecek-Marshall M, Fall R
J Bacteriol . 1993 Nov; 175(22):7216-21. PMID: 8226668
The kinetics of appearance and disappearance of three classes of ice nuclei in Pseudomonas syringae was investigated under conditions where high-level expression of the ice nucleation phenotype was obtained. The...