J A Nolta
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Explore the profile of J A Nolta including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
510
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Recent Articles
1.
Nolta J, Thiemann F, Arakawa-Hoyt J, Dao M, Barsky L, Moore K, et al.
Leukemia
. 2002 Mar;
16(3):352-61.
PMID: 11896538
The immortalized murine stromal cell line AFT024 has been reported to maintain human hematopoietic progenitors in an undifferentiated state in vitro. In the current studies the beige/nude/xid (bnx) mouse in...
2.
3.
Wang X, Dao M, Kuo I, Nolta J
Clin Immunol
. 2001 Aug;
100(3):339-48.
PMID: 11513547
We have previously described extrathymic generation of human T cells from purified stem cells in the bone marrow of athymic immune deficient mice. This system provides a pure population of...
4.
Dao M, Tsark E, Nolta J
Curr Opin Mol Ther
. 2001 Mar;
1(5):553-7.
PMID: 11249661
Animal xenograft models of gene therapy have become increasingly popular to study the effects of various transduction strategies on human hematopoietic stem cells (HSC). Xenograft models provide an in vivo...
5.
Tsark E, Dao M, Wang X, Weinberg K, Nolta J
J Immunol
. 2000 Dec;
166(1):170-81.
PMID: 11123290
The beige/nude/xid/human (bnx/hu) model of human hematopoiesis provides a unique opportunity to study extrathymic human T lymphocyte development in an in vivo system. Purified human hematopoietic stem cells develop into...
6.
Evans M, Jordan C, Chang S, Conrad C, Gerberding J, Kaufman H, et al.
Infect Control Hosp Epidemiol
. 2000 Nov;
21(10):659-73.
PMID: 11083185
Gene therapy is being studied for the treatment of a variety of acquired and inherited disorders. Retroviruses, adenoviruses, poxviruses, adeno-associated viruses, herpesviruses, and others are being engineered to transfer genes...
7.
Dao M, Nolta J
Leukemia
. 2000 May;
14(5):773-6.
PMID: 10803504
Recent evidence suggests that expression of CD34 on the cell membrane does not always correlate with stem cell activity. In the mouse, there is a highly quiescent population of stem...
8.
Arakawa-Hoyt J, Dao M, Thiemann F, Hao Q, Ertl D, Weinberg K, et al.
Bone Marrow Transplant
. 2000 Jan;
24(11):1167-76.
PMID: 10642804
The lack of human B lymphocyte development in beige/nude/XID (bnx) mice is in sharp contrast to the robust development observed in another immune deficient strain, the NOD/SCID mouse. The ability...
9.
Dao M, Nolta J
Curr Opin Immunol
. 1999 Oct;
11(5):532-7.
PMID: 10508705
The past year has brought forth some exciting developments in the use of murine xenotransplantation systems to study the biology and transduction of human hematopoietic stem cells. The effects of...
10.
Liu M, Kant A, Izadi K, Nolta J, Durden D
J Leukoc Biol
. 1999 Apr;
65(4):523-34.
PMID: 10204582
Cbl is a cytosolic protein that is rapidly tyrosine phosphorylated in response to Fc receptor activation and binds to the adaptor proteins Grb2, CrkL, and Nck. A few reports describe...