J A Nadel
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Explore the profile of J A Nadel including associated specialties, affiliations and a list of published articles.
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415
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5771
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Recent Articles
1.
Nadel J, Pawelko S, Scott J, McLaughlin R, Fox M, Ghanem M, et al.
Sci Rep
. 2021 Oct;
11(1):19847.
PMID: 34615966
Habits are inflexible behaviors that develop after extensive repetition, and overreliance on habits is a hallmark of many pathological states. The striatum is involved in the transition from flexible to...
2.
Kalinowski A, Galen B, Ueki I, Sun Y, Mulenos A, Osafo-Addo A, et al.
Mucosal Immunol
. 2018 Feb;
11(3):958-967.
PMID: 29411775
Respiratory syncytial virus (RSV) persists as a significant human pathogen that continues to contribute to morbidity and mortality. In children, RSV is the leading cause of lower respiratory tract infections,...
3.
4.
Bateman E, Rennard S, Barnes P, Dicpinigaitis P, Gosens R, Gross N, et al.
Pulm Pharmacol Ther
. 2009 Jul;
22(6):533-42.
PMID: 19635581
Tiotropium is commonly used in the treatment of chronic obstructive pulmonary disease. Although largely considered to be a long-acting bronchodilator, its demonstrated efficacy in reducing the frequency of exacerbations and...
5.
Epidermal growth factor receptor-mediated innate immune responses and their roles in airway diseases
Burgel P, Nadel J
Eur Respir J
. 2008 Oct;
32(4):1068-81.
PMID: 18827153
Inhaled air is contaminated with pathogens and particulates that may deposit in the airways and damage the host. In response to these invaders, the airway epithelium has developed innate immune...
6.
Berger W, Nadel J
Respir Med
. 2007 Nov;
102(2):173-88.
PMID: 18023995
Formoterol is a selective long-acting beta2-adrenergic receptor agonist (LABA) that provides significant and sustained bronchodilatory effect for up to 12h following a single dose. The onset of effect is significantly...
7.
Burgel P, Nadel J
Thorax
. 2004 Nov;
59(11):992-6.
PMID: 15516478
The epithelial cells lining the airways serve protective functions. The "barrier function" of the epithelium protects the individual from damage by inhaled irritants. The epithelium produces mucins which become hydrated...
8.
Burgel P, Cardell L, Ueki I, Nadel J
Eur Respir J
. 2004 Oct;
24(4):594-600.
PMID: 15459138
Increased mucin expression is a feature of nasal polyposis. Corticosteroids reduce polyp size and symptoms, but their effect on mucin production remains unknown. In this study, the effects of intranasal...
9.
Kohri K, Ueki I, Shim J, Burgel P, Oh Y, Tam D, et al.
Eur Respir J
. 2002 Nov;
20(5):1263-70.
PMID: 12449183
Hypersecretory disease associated with Pseudomonas aeruginosa (PA) infections is characterised by increased goblet cells and increased mucin production. Recently, an epidermal growth factor receptor (EGFR) signalling cascade was shown to...
10.
Nadel J, Burgel P
Curr Opin Pharmacol
. 2001 Nov;
1(3):254-8.
PMID: 11712748
Airway hypersecretion is a serious and presently untreatable symptom of chronic inflammatory airway diseases. Recently, it has been discovered that epithelial growth factor receptor expression and activation causes mucin production...