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J A L Houghton

Explore the profile of J A L Houghton including associated specialties, affiliations and a list of published articles. Areas
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Articles 3
Citations 207
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Recent Articles
1.
De Franco E, Caswell R, Houghton J, Iotova V, Hattersley A, Ellard S
Diabet Med . 2016 Aug; 34(4):582-585. PMID: 27477181
Aims: An early genetic diagnosis of neonatal diabetes guides clinical management and results in improved treatment in ~ 40% of patients. In the offspring of individuals with neonatal diabetes, a...
2.
Ellard S, Lango Allen H, De Franco E, Flanagan S, Hysenaj G, Colclough K, et al.
Diabetologia . 2013 Jun; 56(9):1958-63. PMID: 23771172
Aims/hypothesis: Current genetic tests for diagnosing monogenic diabetes rely on selection of the appropriate gene for analysis according to the patient's phenotype. Next-generation sequencing enables the simultaneous analysis of multiple...
3.
Sansbury F, Flanagan S, Houghton J, Shuixian Shen F, Al-Senani A, Habeb A, et al.
Diabetologia . 2012 Jun; 55(9):2381-5. PMID: 22660720
Aims: The gene SLC2A2 encodes GLUT2, which is found predominantly in pancreas, liver, kidney and intestine. In mice, GLUT2 is the major glucose transporter into pancreatic beta cells, and biallelic...