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J A Hubbell

Explore the profile of J A Hubbell including associated specialties, affiliations and a list of published articles. Areas
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Articles 158
Citations 5493
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Recent Articles
1.
Missirlis D, Hubbell J, Tirelli N
Soft Matter . 2020 Jul; 2(12):1067-1075. PMID: 32680209
Amphiphilic hydrogel nanoparticles, composed of covalently cross-linked Pluronic F127 and PEG, exhibit a temperature- and concentration-dependent gelation in water which is interpreted as a colloidal glass formation. The possible applications...
2.
Vardar E, Vythilingam G, Pinnagoda K, Engelhardt E, Zambelli P, Hubbell J, et al.
Biomaterials . 2019 Mar; 206:41-48. PMID: 30925287
Stress urinary incontinence (SUI) is a life changing condition, affecting 20 million women worldwide. In this study, we developed a bioactive, injectable bulking agent that consists of Permacol™ (Medtronic, Switzerland)...
3.
Larsson H, Vythilingam G, Pinnagoda K, Vardar E, Engelhardt E, Sothilingam S, et al.
Sci Rep . 2018 Jul; 8(1):10057. PMID: 29968749
There is a need for efficient and "off-the-shelf" grafts in urethral reconstructive surgery. Currently available surgical techniques require harvesting of grafts from autologous sites, with increased risk of surgical complications...
4.
Vardar E, Larsson H, Allazetta S, Engelhardt E, Pinnagoda K, Vythilingam G, et al.
Acta Biomater . 2017 Dec; 67:156-166. PMID: 29197579
Statement Of Significance: Urinary incontinence is involuntary urine leakage, resulting from a deficient function of the sphincter muscle complex. Yet there is no functional cure for this devastating condition using...
5.
Vardar E, Larsson H, Engelhardt E, Pinnagoda K, Briquez P, Hubbell J, et al.
Acta Biomater . 2016 Jun; 41:75-85. PMID: 27286676
Unlabelled: Clinical success of bladder reconstructive procedures could be promoted by the availability of functional biomaterials. In this study, we have developed a multi-layered scaffold consisting of a bioactive fibrin...
6.
Sawhney A, Hubbell J
Methods Mol Med . 2011 Mar; 18:85-100. PMID: 21370170
The process of wound healing in internal organs lined with mesothelial cells is different in some respects from healing in cutaneous injuries. Hertzler (1) noted that cutaneous wound re-epithelialization takes...
7.
Patterson J, Hubbell J
Biomaterials . 2010 Nov; 32(5):1301-10. PMID: 21040970
Bioactive hydrogels formed from the Michael-type addition reactions of end-functionalized poly (ethylene glycol) macromers with thiol-containing protease-sensitive peptide crosslinkers have previously been described as matrices for cell-induced enzymatic remodeling. In...
8.
Patterson J, Hubbell J
Biomaterials . 2010 Jul; 31(30):7836-45. PMID: 20667588
Bioactive hydrogels formed by Michael-type addition reactions of end-functionalized poly(ethylene glycol) macromers with cysteine-containing peptides have been described as extracellular matrix mimetics and tissue engineering scaffolds. Although these materials have...
9.
Engelhardt E, Stegberg E, BROWN R, Hubbell J, Wurm F, Adam M, et al.
J Tissue Eng Regen Med . 2009 Oct; 4(2):123-30. PMID: 19842107
Collagen is highly conserved across species and has been used extensively for tissue regeneration; however, its mechanical properties are limited. A recent advance using plastic compression of collagen gels to...
10.
Feller L, Bearinger J, Wu L, Hubbell J, Textor M, Tosatti S
Surf Sci . 2009 Jul; 602(13):2305-2310. PMID: 19578480
Poly(propylene sulfide-bl-ethylene glycol (PPS-PEG) is an amphiphilic block copolymer that spontaneously adsorbs onto gold from solution. This results in the formation of a stable polymeric layer that renders the surface...