J A Dixson
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Explore the profile of J A Dixson including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
24
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Recent Articles
1.
N-Substituted sulfonamide carbonic anhydrase inhibitors with topical effects on intraocular pressure
Duffel M, Ing I, Segarra T, Dixson J, BARFKNECHT C, Schoenwald R
J Med Chem
. 1986 Aug;
29(8):1488-94.
PMID: 3735316
N-Methylacetazolamide was shown to be active topically in reducing intraocular pressure (IOP) to a small but statistically significant level in the normotensive rabbit eye. In vivo experiments with N-methylacetazolamide suggest...
2.
Eller M, Schoenwald R, Dixson J, Segarra T, BARFKNECHT C
J Pharm Sci
. 1985 May;
74(5):525-9.
PMID: 4020628
Ethoxzolamide (1) and two analogues, representing a hydroxyethoxy and a hydrogen substitution on the 6-position of the benzene ring (2 and 3), were applied to rabbit eyes using a topical...
3.
Eller M, Schoenwald R, Dixson J, Segarra T, BARFKNECHT C
J Pharm Sci
. 1985 Feb;
74(2):155-60.
PMID: 3989684
An analogue series representing modification to the benzene ring of ethoxzolamide has been evaluated for solubility, pKa, partitioning, and permeability across excised rabbit corneas. These physical parameters were correlated to...
4.
Schoenwald R, Eller M, Dixson J, BARFKNECHT C
J Med Chem
. 1984 Jun;
27(6):810-2.
PMID: 6737424
Ethoxzolamide and several derivatives (1-6) were synthesized and evaluated for carbonic anhydrase inhibition (CAI), solubility, pKa, distribution, and corneal permeability. The 6-hydroxy (5) and, particularly, the 6-chloro (6) analogues have...