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J A Carcillo

Explore the profile of J A Carcillo including associated specialties, affiliations and a list of published articles. Areas
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Articles 56
Citations 824
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Recent Articles
1.
Aneja R, Carcillo J
Minerva Anestesiol . 2011 Sep; 77(10):986-92. PMID: 21952599
Sepsis is a significant public health problem that affects children and adults alike. Despite some similarities in the approach to pediatric and adult septic shock, there are key differences as...
2.
Wheeler D, Lahni P, Odoms K, Jacobs B, Carcillo J, Doughty L, et al.
Inflamm Res . 2007 Jun; 56(5):216-9. PMID: 17588138
Objective And Design: Recent data suggest that extracellular Hsp60 modulates the host innate immune response. We analyzed plasma Hsp60 levels in children admitted to a level III tertiary care PICU...
3.
Peng Z, Kiss J, Cortese-Hasset A, Carcillo J, Nguyen T, Kellum J
Int J Artif Organs . 2007 Jun; 30(5):401-6. PMID: 17551903
Objectives: Sepsis-induced thrombotic microangiopathy is successfully treated by plasma exchange therapy. However, certain putative mediators of thrombotic microangiopathy may not be removed by plasma filtration. Methods: We conducted an in...
4.
Arkader R, Troster E, Lopes M, Junior R, Carcillo J, Leone C, et al.
Arch Dis Child . 2005 Dec; 91(2):117-20. PMID: 16326799
Aims: To evaluate whether procalcitonin (PCT) and C reactive protein (CRP) are able to discriminate between sepsis and systemic inflammatory response syndrome (SIRS) in critically ill children. Methods: Prospective, observational...
5.
Nguyen T, Stegmayr B, Busund R, Bunchman T, Carcillo J
Int J Artif Organs . 2005 May; 28(5):459-65. PMID: 15883960
Background: Plasma therapies are being applied to thombotic syndromes, but there are limited controlled studies. Objective: To review the evidence and the current practices for plasma therapies in thrombotic syndromes....
6.
Thomas N, Messina J, DeBruin W, Carcillo J
Pediatr Cardiol . 2004 May; 26(1):104-6. PMID: 15136901
Extrarenal involvement manifesting in the cardiovascular system is a rare but potentially fatal complication of hemolytic uremic syndrome (HUS). Current treatment is aimed at cardiovascular supportive measures while awaiting organ...
7.
Han Y, Huang L, Jackson E, Dubey R, Gillepsie D, Carcillo J
Res Commun Mol Pathol Pharmacol . 2002 Jul; 110(1-2):107-16. PMID: 12090349
Sepsis depletes intracellular stores of ATP and NAD+, leading to cellular energy failure. Liposome encapsulation improves intracellular delivery of bulky, charged molecules and substrates susceptible to extracellular enzyme degradation. We...
8.
Robertson C, Bell M, Kochanek P, Adelson P, Ruppel R, Carcillo J, et al.
Crit Care Med . 2002 Jan; 29(12):2287-93. PMID: 11801827
Objectives: To measure adenosine concentration in the cerebrospinal fluid of infants and children after severe traumatic brain injury and to evaluate the contribution of patient age, Glasgow Coma Scale score,...
9.
Tofovic S, Zacharia L, Carcillo J, Jackson E
Shock . 2001 Sep; 16(3):196-202. PMID: 11531021
The purpose of this study was to investigate in vivo the effects of modulating the adenosine system on endotoxin-induced release of cytokines and changes in heart performance and neurohumoral status...
10.
Despond O, Proulx F, Carcillo J, Lacroix J
Curr Opin Pediatr . 2001 Jun; 13(3):247-53. PMID: 11389359
Systemic inflammatory response syndrome may be viewed as the systemic expression of cytokine signals that normally function on an autocrine or paracrine level. Sepsis is defined as systemic inflammatory response...