J A Cancelas
Overview
Explore the profile of J A Cancelas including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
49
Citations
454
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Nayak R, Chang K, Singh A, Kotliar M, Desai M, Wellendorf A, et al.
Nat Commun
. 2022 Jun;
13(1):3056.
PMID: 35650206
Acute B-cell lymphoblastic leukemia (B-ALL) results from oligo-clonal evolution of B-cell progenitors endowed with initiating and propagating leukemia properties. The activation of both the Rac guanine nucleotide exchange factor (Rac...
2.
Nayak R, Hegde S, Althoff M, Wellendorf A, Mohmoud F, Perentesis J, et al.
Nat Commun
. 2019 Jan;
10(1):46.
PMID: 30610188
Epigenetically regulated transcriptional plasticity has been proposed as a mechanism of differentiation arrest and resistance to therapy. BCR-ABL leukemias result from leukemic stem cell/progenitor transformation and represent an opportunity to...
3.
Cancelas J, Gottschall J, Rugg N, Graminske S, Schott M, North A, et al.
Vox Sang
. 2017 Feb;
112(3):210-218.
PMID: 28220519
Background And Objectives: Pathogen reduction technology using amustaline (S-303) was developed to reduce the risk of transfusion-transmitted infection and adverse effects of residual leucocytes. In this study, the viability of...
4.
Privette Vinnedge L, Benight N, Wagh P, Pease N, Nashu M, Serrano-Lopez J, et al.
Oncogene
. 2014 Jun;
34(18):2325-36.
PMID: 24954505
Disease progression and recurrence are major barriers to survival for breast cancer patients. Understanding the etiology of recurrent or metastatic breast cancer and underlying mechanisms is critical for the development...
5.
Raman R, Kumar R, Hinge A, Kumar S, Nayak R, Xu J, et al.
Leukemia
. 2013 Apr;
27(11):2209-19.
PMID: 23563238
Hematopoiesis is regulated by components of the microenvironment, so-called niche. Here, we show that p190-B GTPase-activating protein (p190-B) deletion in mice causes hematopoietic failure during ontogeny, in p190-B(-/-) fetal liver...
6.
Taniguchi Ishikawa E, Chang K, Nayak R, Olsson H, Ficker A, Dunn S, et al.
Nat Commun
. 2013 Apr;
4:1660.
PMID: 23552075
Krüppel-like factor 5 regulates pluripotent stem cell self-renewal, but its role in somatic stem cells is unknown. Here we show that Krüppel-like factor 5-deficient haematopoietic stem cells and progenitors fail...
7.
Cancelas J
Transfusion
. 2011 Nov;
51 Suppl 4:153S-159S.
PMID: 22074626
Rac GTPases form part of the family of Rho small GTPases. Rac GTPases, like other Rho family GTPases, are key molecular switches controlling the transduction of external signals to cytoplasmic...
8.
Cardigan R, van der Meer P, Pergande C, Cookson P, Baumann-Baretti B, Cancelas J, et al.
Transfusion
. 2011 Jan;
51 Suppl 1:50S-57S.
PMID: 21223296
Background: There is increasing international interest in producing components from blood that has been stored at room temperature for 24 hours. The lack of comprehensive data on the quality of...
9.
Miller S, Lan Z, Hardiman A, Wu J, Kordich J, Patmore D, et al.
Oncogene
. 2009 Nov;
29(3):368-79.
PMID: 19901965
Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive sarcomas without effective therapeutics. Bioinformatics was used to identify potential therapeutic targets. Paired Box (PAX), Eyes Absent (EYA), Dachsund (DACH) and Sine...
10.
Sanchez-Aguilera A, Rattmann I, Drew D, Muller L, Summey V, Lucas D, et al.
Leukemia
. 2009 Oct;
24(1):97-104.
PMID: 19847197
RhoH is a hematopoietic-specific, GTPase-deficient member of the Rho GTPase family that functions as a regulator of thymocyte development and T-cell receptor signaling by facilitating localization of zeta-chain-associated protein kinase...