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J-Y Chang

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Articles 32
Citations 521
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Recent Articles
11.
Lee W, Huang C, Chen K, Wong T, Ou C, Tsai S, et al.
Oral Dis . 2014 Apr; 21(2):207-15. PMID: 24724948
Objective: Previous studies examining the association between genetic variations in prostaglandin pathway and risk of head and neck cancer (HNC) have only included polymorphisms in the PTGS2 (COX2) gene. This...
12.
Tsai A, Wang C, Liou J, Pai H, Hsiao C, Chang J, et al.
Cell Death Dis . 2014 Apr; 5:e1162. PMID: 24722287
Microtubule-binding agents, such as taxanes and vinca alkaloids, are used in the treatment of cancer. The limitations of these treatments, such as resistance to therapy and the need for intravenous...
13.
Sheu J, Lee C, Hua C, Li C, Lai M, Lee S, et al.
Oncogene . 2013 Apr; 33(11):1375-84. PMID: 23624915
EGFR overexpression and chromosome 3p deletion are two frequent events in head and neck cancers. We previously mapped the smallest region of recurrent copy-number loss at 3p12.2-p14.1. LRIG1, a negative...
14.
Shiah H, Chen C, Dai C, Hsiao C, Lin Y, Su W, et al.
Aliment Pharmacol Ther . 2012 Nov; 37(1):62-73. PMID: 23134470
Background: Deregulation of mammalian target of rapamycin (mTOR) signalling is common in human hepatocellular carcinoma (HCC). Aim: To determine the maximum tolerated dose (MTD) of the oral mTOR inhibitor everolimus...
15.
Chang J, Chiang M, Lin S, Lee M, He H, Chou P, et al.
Cell Death Dis . 2012 Apr; 3:e302. PMID: 22534828
Self-aggregation of transforming growth factor β (TGF-β)1-induced antiapoptotic factor (TIAF1) is known in the nondemented human hippocampus, and the aggregating process may lead to generation of amyloid β (Aβ) for...
16.
Kim H, Kim Y, Chang J, Ko J, Kho H
Oral Dis . 2012 Apr; 18(6):613-20. PMID: 22533537
Objective: The aim of this study was to investigate salivary markers related with burning mouth syndrome (BMS). Materials And Methods: Thirty female patients with BMS and twenty female control subjects...
17.
Jung K, Chu K, Lee S, Yoon H, Chang J, Nam W, et al.
Clin Pharmacol Ther . 2011 Sep; 90(4):612-9. PMID: 21900887
Clopidogrel therapy to prevent atherothrombosis faces the challenge of reduced responsiveness. The absorption of clopidogrel is regulated by multidrug-resistance protein 1 (MDR1) in the intestinal epithelium. Given that aspirin induces...
18.
Charoenfuprasert S, Yang Y, Lee Y, Chao K, Chu P, Lai C, et al.
Oncogene . 2011 Mar; 30(33):3570-84. PMID: 21399663
Existence of humoral immunity has been previously demonstrated in malignant ascitic fluids. However, only a limited number of immunogenic tumor-associated antigens (TAAs) were identified, and few of which are associated...
19.
Lee M, Lin S, Chang J, Schultz L, Heath J, Hsu L, et al.
Cell Death Dis . 2011 Mar; 1:e110. PMID: 21368882
The role of a small transforming growth factor beta (TGF-β)-induced TIAF1 (TGF-β1-induced antiapoptotic factor) in the pathogenesis of Alzheimer's disease (AD) was investigated. TIAF1 physically interacts with mothers against DPP...
20.
Park M, Chang J, Kang J, Park K, Kho H
Oral Dis . 2010 Mar; 16(4):382-7. PMID: 20233322
Objective: To investigate the viscosity and wettability of hyaluronic acid (HA), its effects on lysozyme and peroxidase activities, and its candidacidal activity. Materials And Methods: Human whole saliva, HA, hen...