J-P Loeffler
Overview
Explore the profile of J-P Loeffler including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
321
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0
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Recent Articles
1.
Echaniz-Laguna A, Bousiges O, Loeffler J, Boutillier A
Curr Med Chem
. 2008 Jun;
15(13):1263-73.
PMID: 18537606
Histone deacetylase (HDAC) inhibition as a therapeutic regimen in motor neuron diseases (MND) is generating intense interest in both the scientific and medical areas, with a number of potent compounds...
2.
Dupuis L, Corcia P, Fergani A, Gonzalez De Aguilar J, Bonnefont-Rousselot D, Bittar R, et al.
Neurology
. 2008 Jan;
70(13):1004-9.
PMID: 18199832
Background: Amyotrophic lateral sclerosis (ALS) is the most serious form of degenerative motor neuron disease in adults, characterized by upper and lower motor neuron degeneration, skeletal muscle atrophy, paralysis, and...
3.
Benosman S, Gross I, Clarke N, Jochemsen A, Okamoto K, Loeffler J, et al.
Cell Death Differ
. 2007 Sep;
14(12):2047-57.
PMID: 17823617
MDMX has been shown to modulate p53 in dividing cells after DNA damage. In this study, we investigated the role of MDMX in primary cultures of neurons undergoing cell death....
4.
Gross I, Armant O, Benosman S, de Aguilar J, Freund J, Kedinger M, et al.
Cell Death Differ
. 2007 Jun;
14(10):1802-12.
PMID: 17599098
Sprouty (Spry) proteins are ligand-inducible inhibitors of receptor tyrosine kinases-dependent signaling pathways, which control various biological processes, including proliferation, differentiation and survival. Here, we investigated the regulation and the role...
5.
Heck N, Garwood J, Loeffler J, Larmet Y, Faissner A
Neuroscience
. 2004 Oct;
129(2):309-24.
PMID: 15501589
We have investigated changes in the extracellular matrix of the hippocampus associated with the early progression of epileptogenesis in a murine model of temporal lobe epilepsy using immunohistochemistry. In the...