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J-F Peyron

Explore the profile of J-F Peyron including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 146
Followers 0
Related Specialties
Oncology
Hematology
Cell Biology
Top 10 Co-Authors
V Imbert
E Griessinger
M Dreano
P Lagadec
Z Neffati
M Nebout
C Frelin
N Gonthier
P Van Houtte
E Verhoeyen
Published In
Leukemia
Cancer Radiother
Cell Death Differ
Affiliations
Soon will be listed here.
Recent Articles
1.
The BMI1 polycomb protein represses cyclin G2-induced autophagy to support proliferation in chronic myeloid leukemia cells
Mourgues L, Imbert V, Nebout M, Colosetti P, Neffati Z, Lagadec P, et al.
Leukemia . 2015 May; 29(10):1993-2002. PMID: 25925206
The BMI1 polycomb protein regulates self-renewal, proliferation and survival of cancer-initiating cells essentially through epigenetic repression of the CDKN2A tumor suppressor locus. We demonstrate here for the first time that...
2.
L-type amino-acid transporter 1 (LAT1): a therapeutic target supporting growth and survival of T-cell lymphoblastic lymphoma/T-cell acute lymphoblastic leukemia
Rosilio C, Nebout M, Imbert V, Griessinger E, Neffati Z, Benadiba J, et al.
Leukemia . 2014 Dec; 29(6):1253-66. PMID: 25482130
The altered metabolism of cancer cells is a treasure trove to discover new antitumoral strategies. The gene (SLC7A5) encoding system L amino-acid transporter 1 (LAT1) is overexpressed in murine lymphoma...
3.
Preclinical targeting of NF-kappaB and FLT3 pathways in AML cells
Griessinger E, Frelin C, Cuburu N, Imbert V, Dageville C, Hummelsberger M, et al.
Leukemia . 2008 Feb; 22(7):1466-9. PMID: 18239622
No abstract available.
4.
Inhibition of the NF-kappaB survival pathway via caspase-dependent cleavage of the IKK complex scaffold protein and NF-kappaB essential modulator NEMO
Frelin C, Imbert V, Bottero V, Gonthier N, Samraj A, Schulze-Osthoff K, et al.
Cell Death Differ . 2007 Oct; 15(1):152-60. PMID: 17932497
Apoptosis is mediated by cysteine-dependent, aspartate-directed proteases of the caspase family that proteolyse strategic intracellular substrates to induce cell suicide. We describe here that engagement of apoptotic processes by Fas...
5.
AS602868, a dual inhibitor of IKK2 and FLT3 to target AML cells
Griessinger E, Imbert V, Lagadec P, Gonthier N, Dubreuil P, Romanelli A, et al.
Leukemia . 2007 Mar; 21(5):877-85. PMID: 17330097
Acute myeloid leukemia (AML) cells carry molecular defects that promote their leukemic proliferation, resistance to apoptosis and defect in differentiation. Pharmacological targeting of the nuclear factor kappaB (NF-kappaB) pathway has...
6.
[Biomodulation of transcriptional factor NF-kappa B by ionizing radiation]
Magne N, Didelot C, Toillon R, Van Houtte P, Peyron J
Cancer Radiother . 2004 Nov; 8(5):315-21. PMID: 15561597
NF-kappaB (Nuclear Factor-kappaB) was described for the first time in 1986 as a nuclear protein binding to the kappa immunoglobulin-light chain enhancer. Since then, NF-kappaB has emerged as an ubiquitous...