Izumi Takeyoshi
Overview
Explore the profile of Izumi Takeyoshi including associated specialties, affiliations and a list of published articles.
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176
Citations
1613
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Recent Articles
1.
Atsumi J, Shimizu K, Ohtaki Y, Kaira K, Kakegawa S, Nagashima T, et al.
J Glob Oncol
. 2017 Jul;
2(1):15-25.
PMID: 28717678
Purpose: A deletion polymorphism of the gene has been reported to be a prognostic factor for patients with non-small-cell lung cancer (NSCLC) treated with epidermal growth factor receptor-tyrosine kinase inhibitors...
2.
Kurozumi S, Matsumoto H, Hayashi Y, Tozuka K, Inoue K, Horiguchi J, et al.
BMC Cancer
. 2017 May;
17(1):354.
PMID: 28532429
Background: The Ki67 labeling index (LI) is regarded as a significant prognostic marker in ER-positive/HER2-negative breast cancer patients. The expression of PgR has recently been identified as another prognostic marker....
3.
Takase Y, Usui K, Shimizu K, Kimura Y, Ichihara T, Ohkawa T, et al.
PLoS One
. 2017 Feb;
12(2):e0171225.
PMID: 28152008
Somatic mutation in human epidermal growth factor receptor-related 2 gene (HER2) is one of the driver mutations in lung cancer. HER2 mutations are found in about 2% of lung adenocarcinomas...
4.
Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, et al.
Nat Commun
. 2016 Aug;
7:12547.
PMID: 27552911
Optineurin (OPTN) mutations cause neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and glaucoma. Although the ALS-associated E478G mutation in the UBAN domain of OPTN reportedly abolishes its NF-κB suppressive activity,...
5.
Takahashi K, Kaira K, Shimizu A, Sato T, Takahashi N, Ogawa H, et al.
Tumour Biol
. 2016 Aug;
37(10):13885-13892.
PMID: 27485115
The β2-adrenergic receptor (β2-AR) is highly expressed in various human neoplasms and has been considered a novel therapeutic target of cancer treatment. However, the clinicopathological significance of β2-AR expression in...
6.
Shimizu K, Nagashima T, Ohtaki Y, Obayashi K, Nakazawa S, Kamiyoshihara M, et al.
Gen Thorac Cardiovasc Surg
. 2016 Jul;
64(10):604-11.
PMID: 27435809
Objective: Thoracic surgeons must be erudite pulmonary vein variation when performing anatomical segmentectomy. We used three-dimensional CT (3DCT) to accumulate variations of the pulmonary veins of the right upper lobe...
7.
Kurozumi S, Yamaguchi Y, Hayashi S, Hiyoshi H, Suda T, Gohno T, et al.
Cancer Med
. 2016 Jun;
5(8):1873-82.
PMID: 27334118
The carboxyl terminus of the Hsc70-interacting protein (CHIP) is considered to induce the ubiquitination and degradation of several oncogenic proteins, and play a role in the inhibition of tumor progression...
8.
Kurozumi S, Padilla M, Kurosumi M, Matsumoto H, Inoue K, Horiguchi J, et al.
Breast Cancer Res Treat
. 2016 Jun;
158(1):99-111.
PMID: 27318853
HER2 gene-protein assay (GPA) is a new method for the simultaneous evaluation of HER2 immunohistochemistry (IHC) and HER2 dual in situ hybridization (DISH) on single tissue sections of breast cancer....
9.
Enokida Y, Shimizu K, Atsumi J, Kakegawa S, Takase Y, Kaira K, et al.
Cancer Med
. 2016 May;
5(8):1791-801.
PMID: 27228500
The MDM2 protein plays an important role in the regulation of cell proliferation and apoptosis via ubiquitination and proteasome-mediated degradation of p53. The genetic polymorphism rs2279744 (c.309T>G) of the MDM2...
10.
Tanaka K, Shimizu K, Kakegawa S, Ohtaki Y, Nagashima T, Kaira K, et al.
Am J Transl Res
. 2016 Apr;
8(1):81-97.
PMID: 27069542
Objectives: Based on recent findings of aromatase and estrogen receptor beta (ERβ) expression in non-small-cell lung cancer, we assessed the clinicopathological and prognostic significance of aromatase and ERβ expression and...