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Iwona A Cymerman

Explore the profile of Iwona A Cymerman including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 601
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Recent Articles
1.
Urbanska M, Gozdz A, Macias M, Cymerman I, Liszewska E, Kondratiuk I, et al.
Mol Neurobiol . 2017 Nov; 55(7):6050-6062. PMID: 29143288
Glycogen synthase kinases-3β (GSK3β) is a key regulator of cell homeostasis. In neurons, GSK3β contributes to control of neuronal transmission and plasticity. Despite extensive studies in non-neuronal cells, crosstalk between...
2.
Gozdz A, Nikolaienko O, Urbanska M, Cymerman I, Sitkiewicz E, Blazejczyk M, et al.
Front Mol Neurosci . 2017 Jul; 10:192. PMID: 28670266
The selective and neuronal activity-dependent degradation of synaptic proteins appears to be crucial for long-term synaptic plasticity. One such protein is activity-regulated cytoskeleton-associated protein (Arc), which regulates the synaptic content...
3.
Wasiak I, Kulikowska A, Janczewska M, Michalak M, Cymerman I, Nagalski A, et al.
PLoS One . 2016 Jan; 11(1):e0146237. PMID: 26752182
Dextran is widely exploited in medical products and as a component of drug-delivering nanoparticles (NPs). Here, we tested whether dextran can serve as the main substrate of NPs and form...
4.
Jasinska M, Milek J, Cymerman I, Leski S, Kaczmarek L, Dziembowska M
Mol Neurobiol . 2015 Aug; 53(7):4701-12. PMID: 26319558
Mir-132 is a neuronal activity-regulated microRNA that controls the morphology of dendritic spines and neuronal transmission. Similar activities have recently been attributed to matrix metalloproteinase-9 (MMP-9), an extrasynaptic protease. In...
5.
Cymerman I, Gozdz A, Urbanska M, Milek J, Dziembowska M, Jaworski J
PLoS One . 2015 Jul; 10(7):e0134018. PMID: 26207897
Although memories appear to be elusive phenomena, they are stored in the network of physical connections between neurons. Dendritic spines, which are actin-rich dendritic protrusions, serve as the contact points...
6.
Knapska E, Macias M, Mikosz M, Nowak A, Owczarek D, Wawrzyniak M, et al.
Proc Natl Acad Sci U S A . 2012 Oct; 109(42):17093-8. PMID: 23027931
The memory of fear extinction is context dependent: fear that is suppressed in one context readily renews in another. Understanding of the underlying neuronal circuits is, therefore, of considerable clinical...
7.
Werner M, Purta E, Kaminska K, Cymerman I, Campbell D, Mittra B, et al.
Nucleic Acids Res . 2011 Feb; 39(11):4756-68. PMID: 21310715
The 5' cap of human messenger RNA consists of an inverted 7-methylguanosine linked to the first transcribed nucleotide by a unique 5'-5' triphosphate bond followed by 2'-O-ribose methylation of the...
8.
Cymerman I, Chung I, Beckmann B, Bujnicki J, Meiss G
Nucleic Acids Res . 2008 Jan; 36(4):1369-79. PMID: 18187503
Evolutionary conserved mitochondrial nucleases are involved in programmed cell death and normal cell proliferation in lower and higher eukaryotes. The endo/exonuclease Nuc1p, also termed 'yeast Endonuclease G (EndoG)', is a...
9.
Schafer P, Cymerman I, Bujnicki J, Meiss G
Protein Sci . 2006 Dec; 16(1):82-91. PMID: 17192590
Lysosomal DNase IIalpha is essential for DNA waste removal and auxiliary apoptotic DNA fragmentation in higher eukaryotes. Despite the key role of this enzyme, little is known about its structure-function...
10.
Cymerman I, Obarska A, Skowronek K, Lubys A, Bujnicki J
Proteins . 2006 Oct; 65(4):867-76. PMID: 17029241
The restriction endonuclease (REase) R. HphI is a Type IIS enzyme that recognizes the asymmetric target DNA sequence 5'-GGTGA-3' and in the presence of Mg(2+) hydrolyzes phosphodiester bonds in both...