Iwen F Grigsby
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Explore the profile of Iwen F Grigsby including associated specialties, affiliations and a list of published articles.
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11
Citations
246
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Recent Articles
1.
Cao S, Maldonado J, Grigsby I, Mansky L, Zhang W
J Virol
. 2014 Dec;
89(4):2430-5.
PMID: 25473052
The particle structure of human T-cell leukemia virus type 1 (HTLV-1) is poorly characterized. Here, we have used cryo-electron tomography to analyze HTLV-1 particle morphology. Particles produced from MT-2 cells...
2.
Fogarty K, Berk S, Grigsby I, Chen Y, Mansky L, Mueller J
J Mol Biol
. 2013 Dec;
426(7):1611-24.
PMID: 24316368
The early events in the retrovirus assembly pathway, particularly the timing and nature of Gag translocation from the site of protein translation to the inner leaflet of the plasma membrane,...
3.
Sun M, Grigsby I, Gorelick R, Mansky L, Musier-Forsyth K
J Virol
. 2013 Nov;
88(2):1271-80.
PMID: 24227839
Retroviral RNA encapsidation involves a recognition event between genomic RNA (gRNA) and one or more domains in Gag. In HIV-1, the nucleocapsid (NC) domain is involved in gRNA packaging and...
4.
Fogarty K, Zhang W, Grigsby I, Johnson J, Chen Y, Mueller J, et al.
Viruses
. 2011 Oct;
3(6):770-93.
PMID: 21994753
Human T-cell leukemia virus type 1 (HTLV-1) has a reputation for being extremely difficult to study in cell culture. The challenges in propagating HTLV-1 has prevented a rigorous analysis of...
5.
Fogarty K, Chen Y, Grigsby I, Macdonald P, Smith E, Johnson J, et al.
Biophys J
. 2011 Mar;
100(6):1587-95.
PMID: 21402042
Fluorescence fluctuation spectroscopy (FFS) quantifies the interactions of fluorescently-labeled proteins inside living cells by brightness analysis. However, the study of cytoplasmic proteins that interact with the plasma membrane is challenging...
6.
Grigsby I, Zhang W, Johnson J, Fogarty K, Chen Y, Rawson J, et al.
Retrovirology
. 2010 Sep;
7:75.
PMID: 20854688
Background: Human T-lymphotropic virus type 1 (HTLV-1) is an important human retrovirus that is a cause of adult T-cell leukemia/lymphoma. While an important human pathogen, the details regarding virus replication...
7.
Grigsby I, Pham L, Mansky L, Gopalakrishnan R, Carlson A, Mansky K
Biochem Biophys Res Commun
. 2010 Feb;
394(1):48-53.
PMID: 20171173
There is strong clinical evidence that implicates tenofovir in the loss of bone mineral density during treatment of human immunodeficiency virus infection. In this study, we sought to test the...
8.
Grigsby I, Pham L, Mansky L, Gopalakrishnan R, Mansky K
Ther Clin Risk Manag
. 2010 Feb;
6:41-7.
PMID: 20169035
Clinical observations have revealed a strong correlation between loss of bone density in HIV-infected individuals, particularly in conjunction with the antiretroviral drug tenofovir, a nucleotide analog that inhibits HIV reverse...
9.
Grigsby I, Pham L, Gopalakrishnan R, Mansky L, Mansky K
Biochem Biophys Res Commun
. 2009 Dec;
391(3):1324-9.
PMID: 20026012
Clinical observations have implicated the antiretroviral drug tenofovir with bone density loss during the management of HIV infection. The goal of this study was to investigate the in vitro effects...
10.
Grigsby I, Rutledge E, Morton C, Finger F
Dev Biol
. 2009 Feb;
329(1):64-79.
PMID: 19233156
Eukaryotic genomes contain either one or two genes encoding homologs of the highly conserved histone chaperone Asf1, however, little is known of their in vivo roles in animal development. UNC-85...