Ivo Buchhalter
Overview
Explore the profile of Ivo Buchhalter including associated specialties, affiliations and a list of published articles.
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Articles
31
Citations
3807
Followers
0
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Recent Articles
1.
Author Correction: Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology
Sturm D, Capper D, Andreiuolo F, Gessi M, Kolsche C, Reinhardt A, et al.
Nat Med
. 2023 Oct;
30(1):306.
PMID: 37875569
No abstract available.
2.
Sturm D, Capper D, Andreiuolo F, Gessi M, Kolsche C, Reinhardt A, et al.
Nat Med
. 2023 Mar;
29(4):917-926.
PMID: 36928815
The large diversity of central nervous system (CNS) tumor types in children and adolescents results in disparate patient outcomes and renders accurate diagnosis challenging. In this study, we prospectively integrated...
3.
Lier A, Penzel R, Heining C, Horak P, Frohlich M, Uhrig S, et al.
JCO Precis Oncol
. 2022 Feb;
2:1-13.
PMID: 35135162
Purpose: Rapidly evolving genomics technologies, in particular comprehensive next-generation sequencing (NGS), have led to exponential growth in the understanding of cancer biology, shifting oncology toward personalized treatment strategies. However, comprehensive...
4.
Horak P, Heining C, Kreutzfeldt S, Hutter B, Mock A, Hullein J, et al.
Cancer Discov
. 2021 Jun;
11(11):2780-2795.
PMID: 34112699
The clinical relevance of comprehensive molecular analysis in rare cancers is not established. We analyzed the molecular profiles and clinical outcomes of 1,310 patients (rare cancers, 75.5%) enrolled in a...
5.
Gajjar A, Robinson G, Smith K, Lin T, Merchant T, Chintagumpala M, et al.
J Clin Oncol
. 2021 Jan;
39(7):822-835.
PMID: 33405951
Purpose: SJMB03 (ClinicalTrials.gov identifier: NCT00085202) was a phase III risk-adapted trial that aimed to determine the frequency and clinical significance of biological variants and genetic alterations in medulloblastoma. Patients And...
6.
Whalley J, Buchhalter I, Rheinbay E, Raine K, Stobbe M, Kleinheinz K, et al.
Nat Commun
. 2020 Oct;
11(1):5040.
PMID: 33028839
Bringing together cancer genomes from different projects increases power and allows the investigation of pan-cancer, molecular mechanisms. However, working with whole genomes sequenced over several years in different sequencing centres...
7.
Waszak S, Robinson G, Gudenas B, Smith K, Forget A, Kojic M, et al.
Nature
. 2020 Apr;
580(7803):396-401.
PMID: 32296180
Cancer genomics has revealed many genes and core molecular processes that contribute to human malignancies, but the genetic and molecular bases of many rare cancers remains unclear. Genetic predisposition accounts...
8.
Goeppert B, Folseraas T, Roessler S, Kloor M, Volckmar A, Endris V, et al.
Hepatology
. 2020 Jan;
72(4):1253-1266.
PMID: 31925805
Background And Aims: Lifetime risk of biliary tract cancer (BTC) in primary sclerosing cholangitis (PSC) may exceed 20%, and BTC is currently the leading cause of death in patients with...
9.
Lambo S, Grobner S, Rausch T, Waszak S, Schmidt C, Gorthi A, et al.
Nature
. 2019 Dec;
576(7786):274-280.
PMID: 31802000
Embryonal tumours with multilayered rosettes (ETMRs) are aggressive paediatric embryonal brain tumours with a universally poor prognosis. Here we collected 193 primary ETMRs and 23 matched relapse samples to investigate...
10.
Feuerbach L, Sieverling L, Deeg K, Ginsbach P, Hutter B, Buchhalter I, et al.
BMC Bioinformatics
. 2019 May;
20(1):272.
PMID: 31138115
Background: Establishment of telomere maintenance mechanisms is a universal step in tumor development to achieve replicative immortality. These processes leave molecular footprints in cancer genomes in the form of altered...